有感觉表现的功能性神经障碍患者的感觉神经动作电位
Sensory nerve action potential in patients with functional neurological disorders with sensory manifestations.
作者信息
Morimoto Kohei, Sekiguchi Kenji, Matsumoto Riki
机构信息
Division of Neurology, Kobe University Graduate School of Medicine, Kobe, Japan.
出版信息
Front Neurol. 2023 Oct 25;14:1259887. doi: 10.3389/fneur.2023.1259887. eCollection 2023.
INTRODUCTION
Functional neurological disorder (FND) has various clinical manifestations. Even though diagnostic criteria for FND have been proposed, FND characteristics with sensory manifestations have not been elucidated. Therefore, we aimed to investigate the association between sensory nerve action potential (SNAP) amplitudes and FND with sensory manifestations.
METHODS
We included 76 outpatients with FND with sensory manifestations whose nerve conduction studies were performed retrospectively. Additionally, we defined 121 patients with other neurological diseases who did not have peripheral neuropathy as disease controls. The SNAP amplitudes were compared between the two groups. We also explored the relationship between SNAP amplitudes and FND-specific clinical symptoms in patients with FND.
RESULTS
No differences were observed in SNAP amplitudes adjusted for age between patients with FND who had sensory manifestations and disease control patients. Additionally, no differences were observed between patients with FND who had and did not have FND-specific clinical symptoms.
CONCLUSION
The SNAP amplitude in patients with FND who had sensory manifestations was equivalent to that in controls.
引言
功能性神经障碍（FND）有多种临床表现。尽管已经提出了FND的诊断标准，但具有感觉表现的FND特征尚未阐明。因此，我们旨在研究感觉神经动作电位（SNAP）振幅与具有感觉表现的FND之间的关联。
方法
我们纳入了76例有感觉表现的FND门诊患者，对其神经传导研究进行回顾性分析。此外，我们定义了121例无周围神经病变的其他神经系统疾病患者作为疾病对照。比较两组之间的SNAP振幅。我们还探讨了FND患者中SNAP振幅与FND特异性临床症状之间的关系。
结果
有感觉表现的FND患者与疾病对照患者之间，经年龄调整后的SNAP振幅没有差异。此外，有和没有FND特异性临床症状的FND患者之间也没有差异。
结论
有感觉表现的FND患者的SNAP振幅与对照组相当。
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