Smith S A, Stallard T J, Littler W A
Cardiovasc Res. 1986 Dec;20(12):877-82. doi: 10.1093/cvr/20.12.877.
A new method for analysing baroreflex sensitivity has been developed. It obviates the mathematical bias inherent in earlier methods and in addition provides a direct measurement of reflex latency. Sensitivity results obtained using this method in 25 patients with a wide range of ages and resting blood pressures were similar to, but consistently lower than, those achieved with the Oxford method. Baroreflex latency results ranged from 650 to 2900 ms (mean(SD) 1084(427) ms) and were reproducible within individuals. Sensitivity results were inversely related to age and resting systolic blood pressure. Reflex latency was not related to these variables or to resting heart rate or reflex sensitivity. This method was able to identify inadequate starting data and greatly reduced the analysis time.
一种分析压力反射敏感性的新方法已被开发出来。它消除了早期方法中固有的数学偏差,此外还能直接测量反射潜伏期。使用该方法在25名年龄和静息血压范围广泛的患者中获得的敏感性结果与牛津方法所取得的结果相似,但始终较低。压力反射潜伏期结果在650至2900毫秒之间(均值(标准差)为1084(427)毫秒),且在个体内部具有可重复性。敏感性结果与年龄和静息收缩压呈负相关。反射潜伏期与这些变量、静息心率或反射敏感性均无关。该方法能够识别不充分的起始数据,并大大缩短了分析时间。