Donuru Achala, Araki Tetsuro, Dako Farouk, Dave Jaydev K, Perez Raul Porto, Xu Dongming, Nachiappan Arun, Barbosa Eduardo Mortani, Noel Peter, Litt Harold, Knollman Friedrich
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Eur J Radiol Open. 2023 Nov 10;11:100538. doi: 10.1016/j.ejro.2023.100538. eCollection 2023 Dec.
To investigate if clinical non-contrast chest CT studies obtained with PCD CT using much lower radiation exposure can achieve the same image quality as with the currently established EID protocol.
MATERIALS/METHODS: A total of seventy-one patients were identified who had a non-contrast chest computed tomography (CT) done on PCD CT and EID CT scanners within a 4-month interval. Five fellowship trained chest radiologists, blinded to the scanner details were asked to review the cases side-by-side and record their preference for images from either the photon-counting-detector (PCD) CT or the energy-integrating detector (EID) CT scanner.
The median CTDIvol for PCD-CT system was 4.710 mGy and EID system was 7.80 mGy (p < 0.001). The median DLP with the PCD-CT was 182.0 mGy.cm and EID system was 262.60 mGy.cm (p < 0.001). The contrast to noise ratio (CNR) was superior on the PCD-CT system 59.2 compared to the EID-CT 53.3; (p < 0.001). Kappa-statistic showed that there was poor agreement between the readers over the image quality from the PCD and EID scanners (κ = 0.19; 95 % CI: 0.12 - 0.27; p < 0.001). Chi-square analysis revealed that 3 out of 5 readers showed a significant preference for images from the PCDCT (p ≤ 0.012). There was no significant difference in the preferences of two readers between EID-CT and PCD-CT images.
The first clinical PCD-CT system allows a significant reduction in radiation exposure while maintaining image quality and image noise using a standardized non-contrast chest CT protocol.
研究使用低得多的辐射剂量通过光子计数探测器（PCD）CT进行的临床非增强胸部CT检查能否获得与当前既定的能量积分探测器（EID）协议相同的图像质量。
材料/方法：共确定71例患者，他们在4个月内分别在PCD CT和EID CT扫描仪上进行了非增强胸部计算机断层扫描（CT）。5名接受过专科培训的胸部放射科医生在不知扫描仪细节的情况下，被要求并排查看病例，并记录他们对光子计数探测器（PCD）CT或能量积分探测器（EID）CT扫描仪图像的偏好。
PCD-CT系统的CTDIvol中位数为4.710 mGy，EID系统为7.80 mGy（p < 0.001）。PCD-CT的DLP中位数为182.0 mGy.cm，EID系统为262.60 mGy.cm（p < 0.001）。PCD-CT系统的对比度噪声比（CNR）优于EID-CT，分别为59.2和53.3（p < 0.001）。kappa统计显示，读者对PCD和EID扫描仪图像质量的一致性较差（κ = 0.19；95% CI：0.12 - 0.27；p < 0.001）。卡方分析显示，5名读者中有3名对PCDCT的图像表现出明显偏好（p ≤ 0.012）。两名读者对EID-CT和PCD-CT图像的偏好没有显著差异。
首个临床PCD-CT系统在使用标准化非增强胸部CT协议时，可显著降低辐射剂量，同时保持图像质量和图像噪声。
