Leadbeater Bonnie J, Merrin Gabriel J, Contreras Alejandra, Ames Megan E
University of Victoria, Victoria, British Columbia.
Syracuse University, Syracuse, New York, USA.
J Can Acad Child Adolesc Psychiatry. 2023 Nov;32(4):224-235. Epub 2023 Nov 1.
Oppositional Defiant Disorder (ODD) is a disruptive behavioral disorder; however, increasing evidence emphasizes irritable mood as a primary symptom of ODD.
This study investigated whether heterogeneous groups (classes) of individuals can be differentiated based on ODD sub-dimensions (irritability and defiance) or on overall ODD symptoms longitudinally. We also examine associations between ODD trajectory class and comorbid substance use (heavy episodic drinking, cannabis use), mental health (depression and anxiety) and behavioral symptoms (ADHD, aggression and substance use) in both adolescence and young adulthood (controlling for adolescent levels of each of these concerns).
Data were from a randomly recruited community sample of 662 Canadian youth (T1 ages 12-18) followed biennially for 10 years (T6 ages 22-29).
Growth mixture models revealed trajectories classes of ODD based on severity of symptoms. A three-class solution provided the best fit with Low ( = 119; 18%), Moderate ( = 473; 71.5%), and High ( = 70; 10.6%) ODD classes. Class trajectory differences were similarity based on symptoms severity (rather than type) for symptom sub-dimensions (irritability defiance). Adolescent and young adult substance use, mental health symptoms, and behavioral problems were significantly higher for the High ODD trajectory class compared to both other classes. Youth in the Moderate ODD trajectory class also showed higher comorbid symptoms in adolescence and young adulthood, compared to the Low ODD trajectory class.
Early identification of children and adolescents with high or moderate ODD symptoms and interventions that simultaneously address defiance and irritability are supported by the findings.
对立违抗障碍(ODD)是一种破坏性行为障碍;然而,越来越多的证据强调易激惹情绪是ODD的主要症状。
本研究纵向调查了能否根据ODD的子维度(易激惹和违抗)或总体ODD症状来区分个体的异质性群体(类别)。我们还研究了ODD轨迹类别与青少年期和青年期的共病物质使用(大量饮酒、大麻使用)、心理健康(抑郁和焦虑)以及行为症状(注意力缺陷多动障碍、攻击行为和物质使用)之间的关联(控制这些问题在青少年期的水平)。
数据来自一个随机招募的662名加拿大青少年的社区样本(T1年龄为12 - 18岁),每两年随访一次,持续10年(T6年龄为22 - 29岁)。
生长混合模型根据症状严重程度揭示了ODD的轨迹类别。一个三类解决方案与低ODD类别(n = 119;18%)、中度ODD类别(n = 473;71.5%)和高ODD类别(n = 70;10.6%)最拟合。类别轨迹差异基于症状子维度(易激惹、违抗)的症状严重程度(而非类型)。与其他两个类别相比,高ODD轨迹类别的青少年和青年期物质使用、心理健康症状及行为问题显著更高。与低ODD轨迹类别相比,中度ODD轨迹类别的青少年在青少年期和青年期也表现出更高的共病症状。
研究结果支持早期识别有高或中度ODD症状的儿童和青少年,并同时针对违抗和易激惹进行干预。