The Department of Child and Adolescent Psychiatry, 4501Leiden University Medical Center, Oegstgeest, the Netherlands.
Youz, Parnassia Group, The Hague, the Netherlands.
Can J Psychiatry. 2021 Jul;66(7):657-666. doi: 10.1177/0706743720974840. Epub 2020 Nov 26.
Oppositional defiant disorder (ODD) consists of irritable and oppositional behaviors, both of which are associated with different problems. However, it is unclear whether irritability and oppositionality enable classification of clinic-referred children and adolescents into mutually exclusive groups (e.g., high in oppositionality, low in irritability), and whether this classification is clinically meaningful.
As part of a clinical protocol, ODD behaviors were assessed at referral through a comprehensive diagnostic interview and questionnaire. Parent- and teacher-reported ODD of 2,185 clinic-referred 5- to 18-year-olds (36.9% females) were used in latent class analysis. Resulting ODD classes were compared, concurrently at referral, and, longitudinally at the end of the diagnostic and treatment process, on various clinically relevant measures that were completed by various informants, including mental health problems, global functioning, and () classifications.
Three classes emerged with high, moderate, and low levels of both irritability and oppositionality. At referral, the high class experienced the highest levels of mental health problems and classifications. Importantly, all ODD classes defined at intake were predictive of diagnostic and treatment outcomes months later. Notably, the high class had higher rates of clinician-based classifications of ODD and conduct disorder, and the lowest levels of pre- and posttreatment global functioning. Additionally, the low class exhibited higher rates of generalized anxiety disorder and fear disorders.
Irritability and oppositionality co-occur in clinic-referred youths to such an extent that classification based on these behaviors does not add to clinical inference. Instead, findings suggest that the overall ODD severity at referral should be used as a guidance for treatment.
对立违抗障碍(ODD)包括易激惹和对立行为,两者都与不同的问题有关。然而,尚不清楚易激惹和对立性是否能够将临床转诊的儿童和青少年分为相互排斥的群体(例如,对立性高,易激惹性低),以及这种分类是否具有临床意义。
作为临床方案的一部分,通过全面的诊断访谈和问卷评估转诊时的 ODD 行为。使用 2185 名临床转诊的 5 至 18 岁(36.9%为女性)儿童和青少年的父母和教师报告的 ODD 进行潜在类别分析。比较得出的 ODD 类别,同时在转诊时进行比较,并在诊断和治疗过程结束时进行比较,使用各种临床相关指标,这些指标由各种信息提供者完成,包括心理健康问题、总体功能和()分类。
三个类别具有高、中、低水平的易激惹和对立性。在转诊时,高水平类别经历了最高水平的心理健康问题和()分类。重要的是,在摄入时定义的所有 ODD 类别都预测了数月后的诊断和治疗结果。值得注意的是,高水平类别具有更高的基于临床医生的 ODD 和品行障碍分类,以及最低的治疗前后总体功能水平。此外,低水平类别表现出更高的广泛性焦虑症和恐惧障碍发生率。
易激惹和对立性在临床转诊的青少年中同时发生,以至于基于这些行为的分类并不能增加临床推断。相反,研究结果表明,转诊时的总体 ODD 严重程度应作为治疗的指导。