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血液透析相关性无阻塞性冠状动脉疾病心肌顿抑:冠状动脉微血管功能障碍的病理生理意义。

Hemodialysis-induced Myocardial Stunning with No Obstructive Coronary Artery Disease: Pathophysiological Significance of Coronary Microvascular Dysfunction.

机构信息

Department of Cardiology, Nagoya City University Graduate School of Medical Sciences, Japan.

Department of Cardiology, Aichi Medical University, Japan.

出版信息

Intern Med. 2024 Jul 15;63(14):2023-2026. doi: 10.2169/internalmedicine.2388-23. Epub 2023 Dec 4.

Abstract

Hemodialysis (HD)-induced myocardial stunning, characterized by transient left ventricular systolic dysfunction during HD, has been reported to be common and associated with a poor prognosis. However, the pathophysiology is not fully understood. We herein report a case of HD-induced myocardial stunning without obstructive coronary artery disease complicated by coronary microvascular dysfunction (CMD), suggesting that CMD plays a crucial role in the pathophysiology of this disease.

摘要

血液透析(HD)相关性心肌顿抑是指 HD 过程中出现短暂性左心室收缩功能障碍,其较为常见,并与不良预后相关。然而,其病理生理学机制尚不完全清楚。本文报道了一例无梗阻性冠状动脉疾病但合并冠状动脉微血管功能障碍(CMD)的 HD 相关性心肌顿抑病例,提示 CMD 在该病的病理生理学中发挥关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93f7/11309868/bf364318d951/1349-7235-63-2023-g001.jpg

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