Agabawi Salem, Tran Vanessa, McEachern James, Walkty Andrew
Department of Internal Medicine, Section of Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Department of Medical Microbiology & Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
J Assoc Med Microbiol Infect Dis Can. 2019 Jun 17;4(2):116-120. doi: 10.3138/jammi.2018-0043. eCollection 2019 Jun.
Gonorrhea is a sexually transmitted infection caused by . The rate of infections in Canada has increased from 2010 to 2015. Disseminated gonococcal infection typically results from bacteremic spread of from a preceding mucosal site of disease (e.g., urogenital). Common clinical manifestations of disseminated gonococcal infection include skin lesions, tenosynovitis, and septic arthritis. Bacterial meningitis as a manifestation of disseminated gonococcal infection has been rarely described. A case of bacterial meningitis due to , complicated by an ischemic stroke, is reported here. Clinical features that may point to as the pathogen in a patient with bacterial meningitis include a concomitant active urogenital infection, skin rash, arthritis, and/or tenosynovitis. Parenteral ceftriaxone for 10 to 14 days combined with a single oral dose of azithromycin is currently recommended as the treatment for gonococcal meningitis in recent guidelines. This case is presented to highlight a potential, albeit rare, complication of a preventable disease that has resurged in the last decade in our community.
淋病是一种由……引起的性传播感染。2010年至2015年期间，加拿大淋病感染率有所上升。播散性淋球菌感染通常是由于淋球菌从先前的黏膜疾病部位（如泌尿生殖系统）发生菌血症扩散所致。播散性淋球菌感染的常见临床表现包括皮肤病变、腱鞘炎和化脓性关节炎。作为播散性淋球菌感染表现的细菌性脑膜炎鲜有报道。本文报告一例由……引起的细菌性脑膜炎，并伴有缺血性中风。在细菌性脑膜炎患者中，可能提示……为病原体的临床特征包括同时存在的活动性泌尿生殖系统感染、皮疹、关节炎和/或腱鞘炎。近期指南目前推荐静脉注射头孢曲松10至14天并联合单次口服阿奇霉素作为淋病性脑膜炎的治疗方法。本病例旨在突出一种可预防疾病在过去十年中在我们社区再度出现的潜在（尽管罕见）并发症。
