Oncology Hematology Urology Department, Oncology Research & Development Unit (UF3596), University Hospital of Martinique, Fort-de-France, Martinique.
Hematology Unit, Oncology Hematology Urology Department, University Hospital of Martinique, Fort-de-France, Martinique.
BMC Cancer. 2023 Dec 6;23(1):1197. doi: 10.1186/s12885-023-11666-9.
A worldwide increased incidence of HM has been marked in recent decades. Therefore, to update epidemiological characteristics of HM in a French West Indies territory, we have performed analysis through Martinique's population-based cancer registry database.
We included cancer case data, from 2009-2018, coded in strict compliance with international standards set by International Agency for Research on Cancer. We calculated standardized incidence rates, cumulative rate (ages 0-74), and temporal trends for cases and deaths using the global population standard, by sex and five age group. Mortality rates were obtained from the French Epidemiology Center on Medical Causes of Death (CépiDc).
One thousand forty seven new cases and 674 deaths from HM were recorded, of which 501 MM (47.8%), 377 LMNH (36%), 123 LAM (11.8%), and 46 LH (4.4%) were reported in both sexes. MM is one of the hematological malignancies with the highest incidence in Martinique among men. Temporal trends of incidence rates for all HM decreased overall in both sexes, except for MM in men. There is significant variability in mortality rates for both sexes. In addition, over the period, the temporal trends of mortality rates for all HMs has decreased overall. Gender-specific rates, between 2009 and 2018, showed that all lymphoid HM have a multimodal distribution curve that increased with age.
Characteristics of HM in Martinique over the reporting periods differ from mainland France. Higher incidences have been observed, particularly for MM, and non-significant sub-mortality is observed compared to mainland France. Moreover, temporal distribution of mortality and incidence trends had decreased over the reporting periods except for MM. Our results showed similarities with African-Americans groups in United States and in particular an equivalence in the frequency distribution of diagnosed HM. However, SMR remains lower compared to US black ethnic groups. Our results contributed to expanding knowledge on the epidemiology of HM with Caribbean data.
近几十年来，全球 HM 的发病率有所上升。因此，为了更新法属西印度群岛领土的 HM 流行病学特征，我们通过马提尼克基于人群的癌症登记数据库进行了分析。
我们纳入了 2009-2018 年的癌症病例数据，这些数据严格按照国际癌症研究机构设定的国际标准进行编码。我们使用全球人口标准，按性别和五个年龄组计算了病例和死亡的标准化发病率、累积率（0-74 岁）和时间趋势。死亡率来自法国流行病学中心关于医疗死因的报告（CépiDc）。
共记录了 1047 例新的 HM 病例和 674 例 HM 死亡病例，其中 501 例 MM（47.8%）、377 例 LMNH（36%）、123 例 LAM（11.8%）和 46 例 LH（4.4%）在男女中均有报告。MM 是马提尼克岛男性中发病率最高的血液系统恶性肿瘤之一。所有 HM 的发病率总体呈下降趋势，除了男性中的 MM。两性的死亡率存在显著差异。此外，在此期间，所有 HM 的死亡率总体呈下降趋势。2009 年至 2018 年期间，性别特异性死亡率显示，所有淋巴造血 HM 的分布曲线呈多峰型，随年龄增长而增加。
报告期内马提尼克岛 HM 的特征与法国大陆不同。观察到更高的发病率，特别是 MM，与法国大陆相比，非显著性亚死亡率较低。此外，除 MM 外，报告期内死亡率和发病率趋势的时间分布均有所下降。我们的结果与美国非裔美国人组相似，尤其是在诊断 HM 的频率分布方面。然而，SMR 仍低于美国黑人族群。我们的结果有助于利用加勒比地区的数据扩展对 HM 流行病学的认识。
