Yang Shiyu, Chen Heming, Su Wei, Luo Yunchun, Liao Jun, Wang Yun, Xiong Liyan, Zhang Chuan, Li Fei, Chen Zhe-Sheng, Wang Tingfang
School of Medicine, Shanghai University, Shanghai, China.
Shanghai Eighth People's Hospital, Shanghai, China.
Front Pharmacol. 2023 Nov 27;14:1297124. doi: 10.3389/fphar.2023.1297124. eCollection 2023.
Ischemia-reperfusion (I/R) injury refers to a new injury caused by reperfusion after the restoration of ischemic tissue or organ blood supply. Salvianic acid A (danshensu) is a primary active ingredient extracted from . It has a protective function against I/R injury in the cardiovascular system, brain, liver, kidney, gastrointestinal tract, and other organs. This article reviews evidence of the protective effects of Salvianic acid A and its potential mechanisms of action in organ I/R injury protection. The aim of this review is to investigate the role of Salvianic acid A in the treatment of I/R injury, providing a reference resource that could facilitate subsequent studies.
缺血再灌注（I/R）损伤是指缺血组织或器官血供恢复后再灌注所导致的一种新的损伤。丹酚酸A（丹参素）是从……中提取的一种主要活性成分。它对心血管系统、脑、肝、肾、胃肠道等器官的I/R损伤具有保护作用。本文综述了丹酚酸A的保护作用证据及其在器官I/R损伤保护中的潜在作用机制。本综述的目的是探讨丹酚酸A在I/R损伤治疗中的作用，提供有助于后续研究的参考资源。
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