Ararso Desalegn, Animut Abebe, Golassa Lemu, Dugassa Sisay
Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Akililu Lemma Institute of Pathobiology, Addis Ababa University, Ethiopia.
Public Health Pract (Oxf). 2023 Nov 22;6:100454. doi: 10.1016/j.puhip.2023.100454. eCollection 2023 Dec.
Currently, evidence synthesis targeting asymptomatic malaria infections in Ethiopia are scarce. This review intended to collect and organize information on asymptomatic malaria.
A Joanna Briggs Institute, scoping review protocol was used. Searches for peer-reviewed articles published between 01 January 2010 and 10 August 2022, were done through a variety of databases, and gray literatures.
17 articles were included out of 7672 articles identified. There was no any longitudinal study to trace forward these asymptomatic malaria cases. The reviewed studies did not address how asymptomatic malaria could be treated. Moreover, living in index houses, their neighbours and family sizes were the main predictors and more associated with onward transmission of malaria. Asymptomatic malaria (ASM) infection might persist in all seasons except June-August, for which data is lacking.
Therefore, as implication of research and policy, it would be necessary to focus on index families and their neighbours in prevention of ASM, conducting longitudinal studies to ascertain when and how many asymptomatic malaria cases without fever during diagnosis would develop clinical malaria. As well, establishing a more sensitive diagnostic technique of malaria surveillance. It is also necessary to provide information regarding the feasibility of treating asymptomatic malaria cases in Ethiopia.
目前,针对埃塞俄比亚无症状疟疾感染的证据综合研究很少。本综述旨在收集和整理有关无症状疟疾的信息。
采用乔安娜·布里格斯研究所的范围综述方案。通过各种数据库和灰色文献搜索2010年1月1日至2022年8月10日期间发表的同行评议文章。
在识别出的7672篇文章中,纳入了17篇。没有任何纵向研究来追踪这些无症状疟疾病例的后续情况。所综述的研究未涉及无症状疟疾如何治疗。此外,居住在索引房屋及其邻居以及家庭规模是主要预测因素,且与疟疾的进一步传播关联更大。除了6月至8月缺乏数据外,无症状疟疾(ASM)感染可能在所有季节持续存在。
因此,作为研究和政策的启示,有必要在预防无症状疟疾方面关注索引家庭及其邻居,开展纵向研究以确定在诊断时无发热的无症状疟疾病例何时以及有多少会发展为临床疟疾。同时,建立更敏感的疟疾监测诊断技术。还需要提供有关在埃塞俄比亚治疗无症状疟疾病例可行性的信息。