RNA疫苗：一项变革性进展。
RNA vaccines: A transformational advance.
作者信息
Brown Brian D, Fauci Anthony S, Belkaid Yasmine, Merad Miriam
机构信息
Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Georgetown University, School of Medicine and McCourt School of Public Policy, Washington, DC, USA.
出版信息
Immunity. 2023 Dec 12;56(12):2665-2669. doi: 10.1016/j.immuni.2023.11.009.
Vaccines have stemmed many infectious diseases, but when SARS-CoV-2 emerged, traditional vaccine development would not have been fast enough. This year's Nobel Prize in Physiology or Medicine recognizes work that enabled the rapid development of mRNA vaccines, which halted the COVID-19 pandemic. The feat was a product of basic biological insights coupled with technological innovations, which have transformed vaccine design.
疫苗已经遏制了许多传染病，但当严重急性呼吸综合征冠状病毒2（SARS-CoV-2）出现时，传统的疫苗研发速度不够快。今年的诺贝尔生理学或医学奖表彰了那些推动信使核糖核酸（mRNA）疫苗快速发展的研究工作，这些疫苗遏制了新冠疫情。这一壮举是基础生物学见解与技术创新相结合的产物，而这些创新改变了疫苗设计。
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