Department of Radiology, Palacky University and University Hospital, Olomouc, Czech Republic.
Fakultní nemocnice Olomouc, Radiologická klinika, Zdravotníků 248/7, 779 00, Olomouc, Czech Republic.
Neuroradiology. 2024 Mar;66(3):305-315. doi: 10.1007/s00234-023-03262-2. Epub 2023 Dec 16.
Currently, with the knowledge of the role of collateral circulation in the development of cerebral ischaemia, traditional therapeutic windows are being prolonged, with time not being the only criterion. Instead, a more personalised approach is applied to select additional patients who might benefit from active treatment. This review briefly describes the current knowledge of the pathophysiology of the development of early ischaemic changes, the capabilities of MRI to depict such changes, and the basics of the routinely used imaging techniques broadly available for the assessment of individual phases of cerebral ischaemia, and summarises the possible clinical use of routine MR imaging, including patient selection for active treatment and assessment of the outcome on the basis of imaging.
目前,随着对侧支循环在脑缺血发展中作用的认识,传统的治疗时间窗正在延长,时间不再是唯一的标准。相反,人们采用更个性化的方法来选择可能从积极治疗中受益的额外患者。这篇综述简要描述了早期缺血性改变发展的病理生理学的当前知识、MRI 描绘这些改变的能力,以及广泛用于评估脑缺血各个阶段的常规成像技术的基础知识,并总结了常规磁共振成像的可能临床应用,包括基于成像选择积极治疗的患者和评估治疗结果。