Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, China.
Maternity and Children Health Care Hospital of Luohu District, Shenzhen, China.
J Psychiatr Res. 2024 Feb;170:47-57. doi: 10.1016/j.jpsychires.2023.11.047. Epub 2023 Dec 10.
To describe the latest disease burden, temporal trends, and risk factors of depressive disorders among young people.
Data from the Global Burden of Disease Study 2019 was utilized to analyze depressive disorders among individuals aged 10-24 years. The study focused on describing the incidence, prevalence, disability-adjusted life years (DALYs), and their attributable risk factors across 204 countries and territories from 2010 to 2019. The estimated annual percentage change (EAPC) was calculated to quantify the temporal trends.
Globally, the incidence, prevalence, and DALYs rate of depressive disorders per 100 000 young people increased from 3003.01, 2445.69, and 448.61 in 2010 to 3035.26, 2470.67, and 452.58 in 2019, indicating a slight upward trend (EAPC = 0.11 for incidence and prevalence; EAPC = 0.09 for DALYs rate). Notably, the percentage of DALYs of depressive disorders among young people increased substantially from 3.24% in 2010 to 3.66% in 2019, an increase of 13.06% (EAPC = 1.26, 95%CI: 1.08-1.44), and the burden of depressive disorders among young people rose from fouth to second in females, and from tenth to fifth in males. Social demographic index (SDI) and other indicators were positively correlated with the percentage of DALYs of depressive disorder and negatively correlated with the EAPC of DALYs.
The global burden of depressive disorders among young people is on the rise. The regional differences in depressive disorders among young people suggest the need for enhanced screening efforts in low-SDI areas, along with the adoption of more effective prevention and control measures.
描述年轻人中抑郁障碍的最新疾病负担、时间趋势和危险因素。
利用 2019 年全球疾病负担研究的数据，分析了年龄在 10-24 岁之间的个体的抑郁障碍。该研究重点描述了 2010 年至 2019 年 204 个国家和地区抑郁障碍的发病率、患病率、伤残调整生命年（DALYs）及其归因危险因素。采用估计年度百分比变化（EAPC）来量化时间趋势。
全球范围内，每 10 万年轻人中抑郁障碍的发病率、患病率和 DALYs 率从 2010 年的 3003.01、2445.69 和 448.61 增加到 2019 年的 3035.26、2470.67 和 452.58，呈轻微上升趋势（发病率和患病率的 EAPC 分别为 0.11；DALYs 率的 EAPC 为 0.09）。值得注意的是，年轻人中抑郁障碍的 DALYs 百分比从 2010 年的 3.24%显著增加到 2019 年的 3.66%，增加了 13.06%（EAPC 为 1.26，95%CI：1.08-1.44），年轻人中抑郁障碍的负担从女性的第四位上升到第二位，从男性的第十位上升到第五位。社会人口指数（SDI）和其他指标与抑郁障碍 DALYs 百分比呈正相关，与 DALYs 的 EAPC 呈负相关。
全球年轻人中抑郁障碍的负担正在上升。年轻人中抑郁障碍的区域差异表明，需要在低 SDI 地区加强筛查工作，并采取更有效的预防和控制措施。
