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强迫症(OCD):关于诊断、共病及治疗方法的全面综述

Obsessive-Compulsive Disorder (OCD): A Comprehensive Review of Diagnosis, Comorbidities, and Treatment Approaches.

作者信息

Singh Abhimanyu, Anjankar Vaibhav P, Sapkale Bhagyesh

机构信息

Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Anatomy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2023 Nov 17;15(11):e48960. doi: 10.7759/cureus.48960. eCollection 2023 Nov.

DOI:10.7759/cureus.48960
PMID:38111433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10726089/
Abstract

Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder widely recognized for its recurrent obsessions and compulsions, which may cause severe impairment worldwide. This review explores the difficulties in diagnosing OCD, its comorbidities, and its treatment approaches. Psychiatry and neuroscience face noteworthy obstacles in treating OCD, which is frequently misdiagnosed and inadequately addressed. This illness, which causes upsetting symptoms that interfere with day-to-day living, affects not only adults but also children and adolescents to a great extent. Despite the availability of multiple therapy methods, such as pharmacological and psychological approaches, many patients exhibit resistance, emphasizing the necessity for alternative therapies. OCD and other psychiatric conditions like bipolar disorder, schizophrenia, and attention deficit hyperactivity disorder substantially overlap, highlighting the complexity of mental health diagnoses. Furthermore, its comorbidity with these diseases further highlights OCD's intricacy. Several therapy considerations have been mentioned, such as using larger dosages of medications and combining different therapeutic approaches. Their association suggests possible common pathogenic pathways between OCD and other psychiatric illnesses. The review concludes that, given the significant number of people who still struggle with chronic symptoms, new treatment techniques and ongoing research are necessary, even in the face of improvements in the understanding and treatment of OCD.

摘要

强迫症(OCD)是一种神经精神疾病,因其反复出现的强迫观念和强迫行为而广为人知,在全球范围内可能导致严重损害。本综述探讨了强迫症诊断中的困难、其共病情况及其治疗方法。精神病学和神经科学在治疗强迫症方面面临着显著障碍,该病经常被误诊且治疗不足。这种疾病会引发干扰日常生活的令人苦恼的症状,不仅在很大程度上影响成年人,也影响儿童和青少年。尽管有多种治疗方法可供使用,如药物治疗和心理治疗,但许多患者表现出抗拒,这凸显了替代疗法的必要性。强迫症与双相情感障碍、精神分裂症和注意力缺陷多动障碍等其他精神疾病有很大重叠,凸显了心理健康诊断的复杂性。此外,它与这些疾病的共病进一步凸显了强迫症的复杂性。文中提到了一些治疗方面的考虑因素,比如使用更大剂量的药物以及结合不同的治疗方法。它们之间的关联表明强迫症与其他精神疾病之间可能存在共同的致病途径。综述得出结论,鉴于仍有大量患者饱受慢性症状之苦,即使在对强迫症的理解和治疗有所改善的情况下,新的治疗技术和持续研究仍然是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bd/10726089/5aced4aa6a1d/cureus-0015-00000048960-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bd/10726089/5aced4aa6a1d/cureus-0015-00000048960-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bd/10726089/5aced4aa6a1d/cureus-0015-00000048960-i01.jpg

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Psychoeducation focused on family accommodation: a practical intervention for parents of children and adolescents with obsessive-compulsive disorder.以家庭接纳为重点的心理教育:针对儿童和青少年强迫症患者父母的一种实用干预措施。
Ital J Pediatr. 2021 Nov 6;47(1):224. doi: 10.1186/s13052-021-01177-3.
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Sexual obsessions in obsessive-compulsive disorder. Definitions, models and cognitive-behavioural therapy.
家族负担:通过代理家庭成员识别强迫症
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Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh.强迫症患者中嗜酸性粒细胞趋化因子-1和白细胞介素-34水平的改变:孟加拉国的一项病例对照观察研究
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Unraveling the Boundaries, Overlaps, and Connections between Schizophrenia and Obsessive-Compulsive Disorder (OCD).解析精神分裂症与强迫症(OCD)之间的界限、重叠及关联
J Clin Med. 2024 Aug 12;13(16):4739. doi: 10.3390/jcm13164739.
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