Chatterjee Shubhangini, G Kaarthikeyan
Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (Deemed to be University), Chennai, IND.
Cureus. 2023 Nov 16;15(11):e48930. doi: 10.7759/cureus.48930. eCollection 2023 Nov.
Background The primary cause of adult tooth loss is commonly attributed to periodontal disease, a condition that weakens the supportive structures around the teeth. In addressing periodontal diseases, surgeons often employ the guided tissue regeneration (GTR) technique, which involves the use of a barrier membrane. Aim The aim of the present study is to assess the composition and mechanical strength of chitosan and eggshell membrane. This research was conducted to provide insights into their potential application in facilitating tissue regeneration. Materials and procedures Chitosan and eggshell membrane were combined to create the membrane. Scanning electron microscopy (SEM) using FEI Quanta FEG 650 SEM (JSM IT-800, JEOL Ltd., Akishima, Tokyo, Japan) was carried out, and mechanical properties were used to measure the parameters of membrane characterization. Results In the dry condition, the membrane's tensile strength was 0.30 MPa and its elongation at break was 8.2%. In the wet condition, the membrane's tensile strength was 0.13 MPa and its elongation at break was 22.6%. The SEM results depicted membrane surface with pore sizes ranging from 16 to 100 meters, and the result obtained from membrane porosity test was 31.2%. Conclusion The chitosan-eggshell membrane exhibited a fibrous surface with a desirable pore size for use as a GTR membrane, but it has low mechanical strength.
背景 成人牙齿脱落的主要原因通常归因于牙周病，这种疾病会削弱牙齿周围的支持结构。在治疗牙周病时，外科医生通常采用引导组织再生（GTR）技术，该技术涉及使用屏障膜。目的 本研究的目的是评估壳聚糖和蛋壳膜的组成和机械强度。进行这项研究是为了深入了解它们在促进组织再生方面的潜在应用。材料和方法 将壳聚糖和蛋壳膜结合制成膜。使用FEI Quanta FEG 650扫描电子显微镜（SEM）（JSM IT - 800，日本电子株式会社，东京秋留岛）进行观察，并使用机械性能来测量膜表征参数。结果 在干燥条件下，膜的拉伸强度为0.30兆帕，断裂伸长率为8.2%。在湿润条件下，膜的拉伸强度为0.13兆帕，断裂伸长率为22.6%。SEM结果显示膜表面孔径范围为16至100微米，膜孔隙率测试结果为31.2%。结论 壳聚糖 - 蛋壳膜呈现出具有理想孔径的纤维状表面，可用作GTR膜，但机械强度较低。
