Huang Liyu, Yu Bo, Sha Yimei, Yao Yihong, Tu Ruiying, Zhao Yao
Beijing Center for Disease Control and Prevention, Beijing 100013, China.
Beijing Fangshan District Center for Disease Control and Prevention, Beijing 102401, China.
Wei Sheng Yan Jiu. 2023 Nov;52(6):924-929. doi: 10.19813/j.cnki.weishengyanjiu.2023.06.011.
To quantitatively assess the concentration and distribution of body iron(BI) in children aged 6 to 17 years in Beijing.
A total of 1392 children aged 6 to 17 years in Beijing were randomly selected for questionnaire survey and physical examination in 2016-2017. Fasting venous blood was collected, serum ferritin(SF) and serum soluble transferrin receptor(sTfR) were measured by immunoturbidimetric assay. BI were calculated, and the concentration and distribution of BI in children aged 6 to 17 years was assessed.
The average BI level of children aged 6 to 17 in Beijing was(5.49±2.94) mg/kg. The average BI level of boys was higher than that of girls, and the average BI level of children with abdominal obesity was higher than that of children without abdominal obesity, and the differences were statistically significant(P<0.05). The concentration of BI in children aged 6 to 17 years in Beijing was 4-7.99 mg/kg, accounting for the highest proportion(57.3%). The concentration of BI<0 mg/kg accounted for the lowest proportion(4.3%). There were significant differences in the distribution of BI concentration in different gender, age and abdominal obesity(P<0.05). The anemia rate of children aged 6 to 17 in Beijing was 2.7%(95%CI 1.9-3.6), the low ferritin rate(SF<25 μg/L) was 22.5%(95%CI 20.0-24.8), and the iron deficiency rate(SF<15 μg/L) was 7.8%(95%CI 6.4-9.3), the negative iron stores(BI<0 mg/kg) rate was 4.3%(95%CI 3.2-5.3). The anemia rate, low ferritin rate, iron deficiency rate and negative iron stores rate were higher in girls than boys, and higher in children aged 12 to 17 years than in children aged 6 to 11 years, and the differences were statistically significant(P<0.01).
Iron deficiency was still present in children aged 6 to 17 in Beijing from 2016 to 2017. The proportion of low BI level in girls and children aged 12 to 17 is higher, respectively.
定量评估北京6至17岁儿童体内铁（BI）的浓度及分布情况。
2016 - 2017年，在北京随机选取1392名6至17岁儿童进行问卷调查和体格检查。采集空腹静脉血，采用免疫比浊法测定血清铁蛋白（SF）和血清可溶性转铁蛋白受体（sTfR）。计算BI，并评估6至17岁儿童BI的浓度及分布情况。
北京6至17岁儿童的平均BI水平为（5.49±2.94）mg/kg。男孩的平均BI水平高于女孩，腹型肥胖儿童的平均BI水平高于非腹型肥胖儿童，差异具有统计学意义（P<0.05）。北京6至17岁儿童的BI浓度为4 - 7.99 mg/kg，占比最高（57.3%）。BI<0 mg/kg的占比最低（4.3%）。不同性别、年龄及腹型肥胖情况的BI浓度分布存在显著差异（P<0.05）。北京6至17岁儿童的贫血率为2.7%（95%CI 1.9 - 3.6），低铁蛋白率（SF<25 μg/L）为22.5%（95%CI 20.0 - 24.8），缺铁率（SF<15 μg/L）为7.8%（95%CI 6.4 - 9.3），铁储备阴性（BI<0 mg/kg）率为4.3%（95%CI 3.2 - 5.3）。女孩中的贫血率、低铁蛋白率、缺铁率及铁储备阴性率均高于男孩，12至17岁儿童高于6至11岁儿童，差异具有统计学意义（P<0.01）。
2016至2017年北京6至17岁儿童仍存在缺铁情况。女孩及12至17岁儿童中低BI水平的比例分别更高。
