Butler M G, Meaney F J
Am J Med Genet. 1987 Feb;26(2):445-55. doi: 10.1002/ajmg.1320260224.
Weight, height, sitting height, and 24 other anthropometric variables (5 body circumferences, skinfolds at 7 sites, 4 head dimensions, and 8 hand and foot measurements) were obtained on 38 Prader-Labhart-Willi syndrome (PLWS) individuals (21 with apparent chromosome 15 deletions and 17 nondeletion cases) with an age range of 2 weeks to 38 1/2 years. More than half of these individuals were measured on more than one occasion. The measurements confirmed the presence of short stature, small hands and feet, obesity, and narrow bi-frontal diameter in PLWS. No differences were found for the anthropometric measurements between the 2 chromosome subgroups. Inverse correlations were produced with linear measurements (eg, height, hand and foot lengths) and age, which indicated a deceleration of linear growth relative to normal individuals with increasing age.
对38名普拉德-拉巴尔特-威利综合征（PLWS）患者（21例有明显的15号染色体缺失，17例无缺失）进行了体重、身高、坐高以及其他24项人体测量变量（5项身体周长、7个部位的皮褶厚度、4项头部尺寸以及8项手足测量）的测量，年龄范围为2周龄至38.5岁。这些个体中超过一半接受了不止一次测量。测量结果证实PLWS患者存在身材矮小、手足短小、肥胖以及双额径狭窄的情况。两个染色体亚组之间的人体测量结果未发现差异。线性测量值（如身高、手足长度）与年龄呈负相关，这表明随着年龄增长，相对于正常个体，线性生长减速。
