口服异维 A 酸治疗寻常痤疮患者对愤怒反应的影响及其与气质的关系。
Effects of oral isotretinoin treatment for acne vulgaris patients on anger responses and the relationship with temperament.
机构信息
Boylam Psychiatric Hospital - Ankara, Turkey.
Department of Dermatology and Venereology - İstanbul, Turkey.
出版信息
Rev Assoc Med Bras (1992). 2023 Dec 18;70(1):e20230592. doi: 10.1590/1806-9282.20230592. eCollection 2023.
OBJECTIVE
Isotretinoin is the only medication against all the factors involved in acne vulgaris pathogenesis. The aim of our study was to verify whether patients with acne vulgaris receiving isotretinoin therapy exhibit elevated anger levels and to observe the correlation between age, temperament traits, and anger.
METHODS
The study group comprised a sum of 100 cases, involving 50 individuals with acne vulgaris-required high-dose retinol therapy and 50 controls who did not start any medication.
RESULTS
Our study showed that anger levels increased with drug use. A positive correlation between cyclothymic temperament, the anxiety-related behavior subdimension, and the introvert and passive-aggressive subdimension of interpersonal anger reactions has been recognized. In addition, a positive one was observed between hyperthymic temperament and the introvert subdimension, which is one of the anger-related thoughts and interpersonal anger reactions.
CONCLUSION
This study elucidates anger dimensions such as anger-related thoughts, behaviors, and reactions in individuals who received retinol treatment for acne vulgaris. In addition to anger and its dimensions, temperament was also investigated. Although several studies have investigated the relationship between acne vulgaris and psychiatric symptoms, to the best of our knowledge, no research has been reported in the English-language literature regarding the relationship between anger dimensions and temperament after retinol treatment that might make our study an original and valuable contribution to the literature.
目的
异维 A 酸是唯一能针对寻常痤疮发病机制中涉及的所有因素的药物。本研究旨在验证接受异维 A 酸治疗的寻常痤疮患者是否存在愤怒水平升高，并观察年龄、气质特征与愤怒之间的相关性。
方法
研究组共 100 例，包括 50 例需要高剂量维 A 酸治疗的寻常痤疮患者和 50 例未开始任何药物治疗的对照组。
结果
我们的研究表明，愤怒水平随药物使用而升高。已经认识到环性气质、与焦虑相关的行为亚维度以及人际愤怒反应的内向和被动攻击亚维度之间存在正相关。此外，还观察到高反应性气质与愤怒相关思维和人际愤怒反应的内向亚维度之间存在正相关。
结论
这项研究阐明了接受维 A 酸治疗寻常痤疮患者的愤怒维度，如愤怒相关的思维、行为和反应。除了愤怒及其维度外，还研究了气质。尽管已有几项研究调查了寻常痤疮与精神症状之间的关系，但据我们所知，在接受维 A 酸治疗后，关于愤怒维度与气质之间的关系的英文文献中尚无报道，这可能使我们的研究成为该领域的原创和有价值的贡献。
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