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玫瑰痤疮与纤维肌痛综合征相关性的“放大”:值得一提吗?

"Zooming" in the association between rosacea and fibromyalgia syndrome: ıs it worth mentioning?

机构信息

Giresun University, Faculty of Medicine, Department of Dermatology and Venereology - Giresun, Turkey.

Giresun University, Faculty of Medicine, Department of Physical Therapy and Rehabilitation - Giresun, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2023 May 29;69(6):e20230256. doi: 10.1590/1806-9282.20230256. eCollection 2023.

Abstract

OBJECTIVE

We aimed to detect the frequency of fibromyalgia syndrome in patients with rosacea and determine whether this frequency was affected by the severity of rosacea and the quality of life.

METHODS

In this prospective, controlled, cross-sectional study, a total of 94 consecutive rosacea cases and 87 age- and sex-matched controls were enrolled. The severity of rosacea was assessed in light of the findings of the National Rosacea Society Ethics Committee. Dermatology Life Quality Index and Rosacea-specific Quality-of-Life instrument had been applied to the cases of rosacea. The diagnosis of fibromyalgia syndrome was established according to the 2016 revised fibromyalgia diagnostic criteria, and the Fibromyalgia Impact Questionnaire was used to determine the functional disability.

RESULTS

The frequency of fibromyalgia syndrome was higher in the rosacea group than in the control group (p=0.01), and Dermatology Life Quality Index and Rosacea-specific Quality-of-Life instrument were higher in patients with rosacea with fibromyalgia syndrome (p=0.006 and p=0.004, respectively). A statistically significant weak positive correlation was observed between Dermatology Quality-of-Life Index, Rosacea-specific Quality-of-Life instrument, and Fibromyalgia Impact Questionnaire; symptom severity scale scores; and fibromyalgia score (r=0.35, r=0.259, and r=0.32 and r=0.376, r=0.305, and r=0.312, respectively).

CONCLUSION

The patients with rosacea have higher rates and disability scores of fibromyalgia syndrome than healthy controls, independent of rosacea severity, and quality of life is correlated with fibromyalgia scores. We might point out that fibromyalgia syndrome accompanying rosacea has more restrictions in their daily routine activities than rosacea alone. As such, physicians should be aware of the possible coexistence of rosacea and fibromyalgia syndrome.

摘要

目的

本研究旨在检测红斑痤疮患者中纤维肌痛综合征的发生率,并确定其发生率是否受到红斑痤疮严重程度和生活质量的影响。

方法

本前瞻性、对照、横断面研究共纳入 94 例连续红斑痤疮患者和 87 名年龄和性别匹配的对照。根据国家红斑痤疮学会伦理委员会的研究结果评估红斑痤疮的严重程度。采用皮肤病生活质量指数和红斑痤疮特异性生活质量量表评估红斑痤疮病例。根据 2016 年修订的纤维肌痛综合征诊断标准诊断纤维肌痛综合征,并采用纤维肌痛影响问卷确定功能障碍。

结果

红斑痤疮组纤维肌痛综合征的发生率高于对照组(p=0.01),且红斑痤疮伴纤维肌痛综合征患者的皮肤病生活质量指数和红斑痤疮特异性生活质量量表评分更高(p=0.006 和 p=0.004)。皮肤病生活质量指数、红斑痤疮特异性生活质量量表和纤维肌痛影响问卷之间存在统计学上的弱正相关(r=0.35、r=0.259、r=0.32 和 r=0.376、r=0.305、r=0.312)。

结论

与健康对照组相比,红斑痤疮患者的纤维肌痛综合征发生率和残疾评分更高,与红斑痤疮严重程度和生活质量无关,且生活质量与纤维肌痛评分相关。我们可能指出,伴有红斑痤疮的纤维肌痛综合征比单纯红斑痤疮在日常生活活动中受到更多限制。因此,医生应注意红斑痤疮和纤维肌痛综合征可能同时存在。

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