Pan Liben, Yang Nan, Sui Yushu, Li Yi, Zhao Wen, Zhang Liqiu, Mu Liqiang, Tang Zhonghua
School of Forestry, Northeast Forestry University, Harbin 150040, China.
Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
Metabolites. 2023 Dec 9;13(12):1193. doi: 10.3390/metabo13121193.
( Miq. f. (Nakai) C. Y. Cheng et C. S. Yang) is a medicinal plant that contains asarinin and sesamin, which possess extensive medicinal value. The adaptation and distribution of 's plant growth are significantly affected by altitude. Although most studies on have concentrated on its pharmacological activities, little is known about its growth and metabolites with respect to altitude. In this study, the physiology, ionomics, and metabolomics were investigated and conducted on the leaves and roots of along an altitude gradient, and the content of its medicinal components was determined. The results showed that soil pH and temperature both decreased along the altitude, which restricts the growth of . The accumulation of TOC, Cu, Mg, and other mineral elements enhanced the photosynthetic capacity and leaf plasticity of in high-altitude areas. A metabolomics analysis revealed that, at high altitude, nitrogen metabolism in leaves was enhanced, while carbon metabolism in roots was enhanced. Furthermore, the metabolic pathways of some phenolic substances, including syringic acid, vanillic acid, and ferulic acid, were altered to enhance the metabolism of organic acids. The study uncovered the growth and metabolic responses of to varying altitudes, providing a theoretical foundation for the utilization and cultivation of .
（米克氏变种（中井）郑CY和杨CS）是一种药用植物，含有细辛脂素和芝麻素，具有广泛的药用价值。该植物生长的适应性和分布受海拔高度的显著影响。尽管大多数关于它的研究都集中在其药理活性上，但关于其在不同海拔高度下的生长和代谢产物却知之甚少。在本研究中，沿着海拔梯度对该植物的叶和根进行了生理、离子组学和代谢组学研究，并测定了其药用成分的含量。结果表明，土壤pH值和温度均随海拔升高而降低，这限制了该植物的生长。总有机碳、铜、镁等矿质元素的积累增强了该植物在高海拔地区的光合能力和叶片可塑性。代谢组学分析表明，在高海拔地区，叶片中的氮代谢增强，而根中的碳代谢增强。此外，一些酚类物质（包括丁香酸、香草酸和阿魏酸）的代谢途径发生改变，以增强有机酸的代谢。该研究揭示了该植物对不同海拔高度的生长和代谢响应，为其利用和栽培提供了理论基础。
