Department of Veterinary Science, National Institute of Infectious Diseases (NIID), Tokyo 162-8640, Japan.
Faculty of Veterinary Technology, Kasetsart University, Bangkok 10900, Thailand.
Viruses. 2023 Dec 11;15(12):2403. doi: 10.3390/v15122403.
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonotic disease caused by the SFTS virus (SFTSV). In Thailand, three human cases of SFTS were reported in 2019 and 2020, but there was no report of SFTSV infection in animals. Our study revealed that at least 16.6% of dogs in Thailand were seropositive for SFTSV infection, and the SFTSV-positive dogs were found in several districts in Thailand. Additionally, more than 70% of the serum samples collected at one shelter possessed virus-neutralization antibodies against SFTSV and the near-complete genome sequences of the SFTSV were determined from one dog in the shelter. The dog SFTSV was genetically close to those from Thailand and Chinese patients and belonged to genotype J3. These results indicated that SFTSV has already spread among animals in Thailand.
严重发热伴血小板减少综合征（SFTS）是一种由 SFTS 病毒（SFTSV）引起的新发蜱传动物源性传染病。在泰国，2019 年和 2020 年报告了 3 例人类 SFTS 病例，但没有动物感染 SFTSV 的报告。我们的研究表明，泰国至少有 16.6%的犬血清呈 SFTSV 感染阳性，SFTSV 阳性犬在泰国多个地区均有发现。此外，在一个收容所采集的血清样本中，超过 70%的样本对 SFTSV 具有病毒中和抗体，并且从该收容所的一只犬中确定了 SFTSV 的近全长基因组序列。该犬 SFTSV 与来自泰国和中国患者的病毒株遗传关系密切，属于基因型 J3。这些结果表明，SFTSV 已在泰国的动物中传播。
