Negoro N, Kanayama Y, Yasuda M, Okamura M, Amatsu K, Koda S, Takeda T, Inoue T
Arthritis Rheum. 1987 Jan;30(1):97-101. doi: 10.1002/art.1780300114.
We performed immunopathologic studies of the pericarditis present in a patient with mixed connective tissue disease. A large number of nuclear RNP (nRNP) immune complexes (ICs) were found in the pericardial fluid, but not in the serum. The pericardial small vessels had no deposits of IgG. These results suggest that locally formed nRNP ICs were closely associated with the pathogenesis of pericarditis in this patient.
我们对一名混合性结缔组织病患者出现的心包炎进行了免疫病理学研究。在心包积液中发现了大量核核糖核蛋白（nRNP）免疫复合物（ICs），但血清中未发现。心包小血管没有IgG沉积。这些结果表明，局部形成的nRNP ICs与该患者心包炎的发病机制密切相关。
