• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

弥合差距：角膜生物工程和再生的前景。

Bridging the gap: The promise of corneal bioengineering and regeneration.

机构信息

Dr. Shroff's Charity Eye Hospital, Daryaganj, Delhi, India.

Shroff Pandorum Centre for Ocular Regeneration, Daryaganj, Delhi, India.

出版信息

Indian J Ophthalmol. 2024 Apr 1;72(4):483-488. doi: 10.4103/IJO.IJO_2084_23. Epub 2023 Dec 26.

DOI:10.4103/IJO.IJO_2084_23
PMID:38146983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11149518/
Abstract

In recent years, significant advances in tissue engineering and regenerative medicine have led to innovative approaches in addressing the various challenges associated with corneal transplants using bioengineered corneas. This mini-review aims to introduce the general ophthalmologist to the concept and technique of bioengineered cornea and provide an overview of the developments so far and an insight into the future direction. By summarizing the latest research and current limitations, we aim to highlight their potential for the future in ultimately contributing to vision restoration.

摘要

近年来，组织工程学和再生医学领域的重大进展为解决生物工程角膜在角膜移植中遇到的各种挑战提供了新方法。本综述旨在向普通眼科医生介绍生物工程角膜的概念和技术，并概述其迄今为止的发展情况和未来方向。通过总结最新的研究和目前的局限性，我们旨在强调它们在未来为恢复视力做出贡献的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c4/11149518/71757fe2aa8f/IJO-72-483-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c4/11149518/4795ccfb1caa/IJO-72-483-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c4/11149518/71757fe2aa8f/IJO-72-483-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c4/11149518/4795ccfb1caa/IJO-72-483-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c4/11149518/71757fe2aa8f/IJO-72-483-g002.jpg

相似文献

1
Bridging the gap: The promise of corneal bioengineering and regeneration.弥合差距：角膜生物工程和再生的前景。
Indian J Ophthalmol. 2024 Apr 1;72(4):483-488. doi: 10.4103/IJO.IJO_2084_23. Epub 2023 Dec 26.
2
Regenerative approaches for the cornea.角膜的再生方法。
J Intern Med. 2016 Sep;280(3):276-86. doi: 10.1111/joim.12502. Epub 2016 Apr 20.
3
Mechanical Properties of Bioengineered Corneal Stroma.生物工程角膜基质的力学性能
Adv Healthc Mater. 2021 Oct;10(20):e2100972. doi: 10.1002/adhm.202100972. Epub 2021 Aug 8.
4
Bioengineering Approaches for Corneal Regenerative Medicine.生物工程方法在角膜再生医学中的应用。
Tissue Eng Regen Med. 2020 Oct;17(5):567-593. doi: 10.1007/s13770-020-00262-8. Epub 2020 Jul 21.
5
Bioengineered corneas: how close are we?生物工程角膜：我们距离成功还有多远？
Curr Opin Ophthalmol. 2003 Aug;14(4):192-7. doi: 10.1097/00055735-200308000-00004.
6
Regenerative approaches as alternatives to donor allografting for restoration of corneal function.再生方法作为替代供体同种异体移植的选择，以恢复角膜功能。
Ocul Surf. 2012 Jul;10(3):170-83. doi: 10.1016/j.jtos.2012.04.004. Epub 2012 May 9.
7
Innervation in corneal bioengineering.角膜生物工程中的神经支配。
Acta Biomater. 2024 Nov;189:73-87. doi: 10.1016/j.actbio.2024.10.009. Epub 2024 Oct 10.
8
Artificial corneas: a regenerative medicine approach.人工角膜：再生医学方法。
Eye (Lond). 2009 Oct;23(10):1985-9. doi: 10.1038/eye.2008.409. Epub 2009 Jan 16.
9
Biomaterials for corneal bioengineering.角膜生物工程用生物材料。
Biomed Mater. 2018 Mar 6;13(3):032002. doi: 10.1088/1748-605X/aa92d2.
10
Corneal regeneration: A review of stromal replacements.角膜再生：基质替代物综述。
Acta Biomater. 2018 Mar 15;69:31-41. doi: 10.1016/j.actbio.2018.01.023. Epub 2018 Feb 1.

引用本文的文献

1
Development of Novel Squid Gladius Biomaterials for Cornea Tissue Engineering.用于角膜组织工程的新型鱿鱼角质材料的研发
Mar Drugs. 2024 Nov 28;22(12):535. doi: 10.3390/md22120535.
2
Harnessing Corneal Stromal Regeneration for Vision Restoration: A Comprehensive Review of the Emerging Treatment Techniques for Keratoconus.利用角膜基质再生恢复视力：圆锥角膜新兴治疗技术的综合综述
Cureus. 2024 Sep 21;16(9):e69835. doi: 10.7759/cureus.69835. eCollection 2024 Sep.

本文引用的文献

1
Assessment of the effects of intrastromal injection of adipose-derived stem cells in keratoconus patients.圆锥角膜患者基质内注射脂肪源性干细胞的效果评估。
Int J Ophthalmol. 2023 Jun 18;16(6):863-870. doi: 10.18240/ijo.2023.06.05. eCollection 2023.
2
Optically Clear Silk Fibroin Films with Tunable Properties for Potential Corneal Tissue Engineering Applications: A Process-Property-Function Relationship Study.用于潜在角膜组织工程应用的具有可调性能的光学透明丝素蛋白膜：工艺-性能-功能关系研究
ACS Omega. 2022 Aug 17;7(34):29634-29646. doi: 10.1021/acsomega.2c01579. eCollection 2022 Aug 30.
3
Bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts.
生物工程角膜组织用于在两个临床队列中的晚期圆锥角膜的微创视力恢复。
Nat Biotechnol. 2023 Jan;41(1):70-81. doi: 10.1038/s41587-022-01408-w. Epub 2022 Aug 11.
4
Blindness and visual impairment and their causes in India: Results of a nationally representative survey.印度的盲症和视力损伤及其原因：一项全国代表性调查的结果。
PLoS One. 2022 Jul 21;17(7):e0271736. doi: 10.1371/journal.pone.0271736. eCollection 2022.
5
Silk Fibroin-Based Biomaterials for Tissue Engineering Applications.丝素蛋白基生物材料在组织工程中的应用。
Molecules. 2022 Apr 25;27(9):2757. doi: 10.3390/molecules27092757.
6
Review of the Current Trends in Clinical Trials Involving Induced Pluripotent Stem Cells.诱导多能干细胞临床试验的当前趋势综述。
Stem Cell Rev Rep. 2022 Jan;18(1):142-154. doi: 10.1007/s12015-021-10262-3. Epub 2021 Sep 16.
7
Regenerative therapy for the Cornea.角膜再生疗法
Prog Retin Eye Res. 2022 Mar;87:101011. doi: 10.1016/j.preteyeres.2021.101011. Epub 2021 Sep 14.
8
Efficacy of Lamellar Keratoplasty with Acellular Porcine Corneal Stroma in Treatment for Infectious Central and Peripheral Corneal Ulcers.脱细胞猪角膜基质板层角膜移植术治疗感染性中央及周边角膜溃疡的疗效
Ther Clin Risk Manag. 2021 Jun 10;17:623-634. doi: 10.2147/TCRM.S309742. eCollection 2021.
9
Corneal Stromal Regeneration: A Review of Human Clinical Studies in Keratoconus Treatment.角膜基质再生：圆锥角膜治疗中人类临床研究综述
Front Med (Lausanne). 2021 Feb 23;8:650724. doi: 10.3389/fmed.2021.650724. eCollection 2021.
10
Corneal Stromal Regeneration Therapy for Advanced Keratoconus: Long-term Outcomes at 3 Years.角膜基质再生疗法治疗晚期圆锥角膜：3 年的长期疗效。
Cornea. 2021 Jun 1;40(6):741-754. doi: 10.1097/ICO.0000000000002646.