Department of Urology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Department of Urology, Affiliated Dongfang Hospital of Xiamen University, Fuzhou, China.
Minim Invasive Ther Allied Technol. 2024 Feb;33(1):51-57. doi: 10.1080/13645706.2023.2286241. Epub 2024 Feb 2.
To compare the effect and safety of retroperitoneal laparoscopic pyelolithotomy (RLP) and percutaneous nephrolithotomy (PCNL) for large pelvis calculi with chronic kidney disease (CKD).
Between June 2017 and July 2021, 62 patients with CKD and large renal pelvis calculi (>4 cm) were treated with RLP. Another 62 patients receiving PCNL served as controls. The perioperative parameters were compared. All patients were followed up for at least 6 months with the stone-free rate and the recovery of renal function evaluated.
Significantly longer operation time (101.47 ± 9.25 vs 62.55 ± 7.54 min), less drop in hemoglobin level (0.90 ± 0.38 vs 2.13 ± 0.80 g/dl), staged operations (0% vs 12.9%), postoperative fever (3.23% vs 16.13%) and delayed bowel movement (3.23% vs 14.52), and shorter hospitalization time (3.90 ± 1.66 vs 4.72 ± 1.80 days) were observed in the RLP group ( < 0.05). The stone-free rates were 100% in the RLP group and 88.7% in the PCNL group at the 3-months follow-up ( < 0.05). The serum creatinine level was significantly lower in the RLP group at 24 h (2.81 ± 1.18 vs 3.00 ± 1.15 mg/dl) and 1 week (2.08 ± 1.13 vs 2.34 ± 1.01 mg/dl) postoperatively ( < 0.05).
Although associated with a longer operation time, RLP is a safer and more efficient surgical option for CKD patients with large pelvic stones than PCNL.
比较后腹腔镜肾盂切开取石术(RLP)与经皮肾镜取石术(PCNL)治疗慢性肾脏病(CKD)合并大肾盂结石的效果和安全性。
2017 年 6 月至 2021 年 7 月,62 例 CKD 合并大肾盂结石(>4cm)患者行 RLP 治疗。同期 62 例行 PCNL 治疗作为对照组。比较围手术期参数。所有患者均至少随访 6 个月,评估结石清除率和肾功能恢复情况。
RLP 组手术时间明显延长(101.47±9.25min 比 62.55±7.54min),血红蛋白下降程度较轻(0.90±0.38g/dl 比 2.13±0.80g/dl),分期手术比例较低(0%比 12.9%),术后发热比例较低(3.23%比 16.13%),术后排便延迟比例较低(3.23%比 14.52%),住院时间较短(3.90±1.66d 比 4.72±1.80d)( < 0.05)。RLP 组 3 个月随访结石清除率为 100%,PCNL 组为 88.7%( < 0.05)。RLP 组术后 24h(2.81±1.18mg/dl 比 3.00±1.15mg/dl)和 1 周(2.08±1.13mg/dl 比 2.34±1.01mg/dl)时血清肌酐水平均显著低于 PCNL 组( < 0.05)。
虽然手术时间较长,但与 PCNL 相比,RLP 是治疗 CKD 合并大肾盂结石患者更安全、更有效的手术选择。