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使用深度学习技术创建高分辨率3D颅骨植入物几何形状。

Creating high-resolution 3D cranial implant geometry using deep learning techniques.

作者信息

Wu Chieh-Tsai, Yang Yao-Hung, Chang Yau-Zen

机构信息

Department of Neurosurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.

College of Medicine, Chang Gung University, Taoyuan, Taiwan.

出版信息

Front Bioeng Biotechnol. 2023 Dec 11;11:1297933. doi: 10.3389/fbioe.2023.1297933. eCollection 2023.

DOI:10.3389/fbioe.2023.1297933
PMID:38149174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10750412/
Abstract

Creating a personalized implant for cranioplasty can be costly and aesthetically challenging, particularly for comminuted fractures that affect a wide area. Despite significant advances in deep learning techniques for 2D image completion, generating a 3D shape inpainting remains challenging due to the higher dimensionality and computational demands for 3D skull models. Here, we present a practical deep-learning approach to generate implant geometry from defective 3D skull models created from CT scans. Our proposed 3D reconstruction system comprises two neural networks that produce high-quality implant models suitable for clinical use while reducing training time. The first network repairs low-resolution defective models, while the second network enhances the volumetric resolution of the repaired model. We have tested our method in simulations and real-life surgical practices, producing implants that fit naturally and precisely match defect boundaries, particularly for skull defects above the Frankfort horizontal plane.

摘要

定制颅骨修补植入物成本高昂且在美学上具有挑战性,尤其是对于大面积的粉碎性骨折。尽管二维图像补全的深度学习技术取得了重大进展,但由于三维颅骨模型的维度更高且计算需求更大,生成三维形状的图像修复仍然具有挑战性。在此,我们提出一种实用的深度学习方法,可从CT扫描创建的有缺陷三维颅骨模型生成植入物几何形状。我们提出的三维重建系统由两个神经网络组成,可生成适用于临床的高质量植入物模型,同时减少训练时间。第一个网络修复低分辨率的缺陷模型,而第二个网络提高修复模型的体积分辨率。我们已在模拟和实际手术操作中测试了我们的方法,所生产的植入物贴合自然且能精确匹配缺损边界,特别是对于法兰克福水平面以上的颅骨缺损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/246290067896/fbioe-11-1297933-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/fa6c200cc67a/fbioe-11-1297933-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/58af8b5081e6/fbioe-11-1297933-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/246290067896/fbioe-11-1297933-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/fa6c200cc67a/fbioe-11-1297933-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/58af8b5081e6/fbioe-11-1297933-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0254/10750412/246290067896/fbioe-11-1297933-g011.jpg

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本文引用的文献

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Back to the Roots: Reconstructing Large and Complex Cranial Defects using an Image-based Statistical Shape Model.回归本源:基于图像的统计形状模型在大型复杂颅骨缺损中的应用。
J Med Syst. 2024 May 23;48(1):55. doi: 10.1007/s10916-024-02066-y.
2
Three-dimensional deep learning to automatically generate cranial implant geometry.三维深度学习自动生成颅骨植入物几何形状。
Sci Rep. 2022 Feb 17;12(1):2683. doi: 10.1038/s41598-022-06606-9.
3
: Database of 500 high-resolution healthy human skulls and 29 craniotomy skulls and implants.包含500个高分辨率健康人类头骨以及29个开颅手术头骨和植入物的数据库。
Data Brief. 2021 Nov 4;39:107524. doi: 10.1016/j.dib.2021.107524. eCollection 2021 Dec.
4
Automatic skull defect restoration and cranial implant generation for cranioplasty.颅骨修复术的自动颅骨缺损修复和颅骨植入物生成。
Med Image Anal. 2021 Oct;73:102171. doi: 10.1016/j.media.2021.102171. Epub 2021 Jul 20.
5
Text Data Augmentation for Deep Learning.用于深度学习的文本数据增强
J Big Data. 2021;8(1):101. doi: 10.1186/s40537-021-00492-0. Epub 2021 Jul 19.
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Reproducibility of CT-based radiomic features against image resampling and perturbations for tumour and healthy kidney in renal cancer patients.基于 CT 的放射组学特征在肾癌患者的肿瘤和健康肾脏的图像重采样和干扰方面的可重复性。
Sci Rep. 2021 Jun 2;11(1):11542. doi: 10.1038/s41598-021-90985-y.
7
- Dataset for automatic cranial implant design and a benchmark for volumetric shape learning tasks.用于自动颅骨植入物设计的数据集以及体积形状学习任务的基准。
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