Baldwin R C, Jolley D J
Br J Psychiatry. 1986 Nov;149:574-83. doi: 10.1192/bjp.149.5.574.
The initial features and progress of depressive symptomatology over 42 to 104 months are presented for 100 elderly patients admitted with severe, non-neurotic depressive states; none had experienced a previous hypomanic episode. Sixty per cent either remained well throughout or had further episodes followed by full recovery; only 7% suffered continuous depressive symptoms. Of potential prognostic factors, only male sex and poor physical health, both at presentation and developing subsequently, were associated with poorer outcomes. The view is supported that treatment with well established methods achieves worthwhile and sustained improvement for most patients.
本文呈现了100例因严重非神经症性抑郁状态入院的老年患者在42至104个月期间抑郁症状的初始特征及进展情况；这些患者均未曾经历过先前的轻躁狂发作。60%的患者在整个期间病情稳定或经历进一步发作后完全康复；仅有7%的患者持续存在抑郁症状。在潜在的预后因素中，仅男性性别以及在就诊时和随后出现的身体健康状况不佳与较差的预后相关。这一观点得到了支持，即采用成熟方法进行治疗能使大多数患者获得有价值且持续的改善。
