Zimmerman M, Pfohl B, Stangl D, Coryell W
Br J Psychiatry. 1986 Nov;149:627-30. doi: 10.1192/bjp.149.5.627.
The Newcastle diagnostic index was completed on 159 depressed in-patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after controlling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.
对159名住院抑郁症患者进行了纽卡斯尔诊断指数评估，这些患者在住院的第一周接受了地塞米松抑制试验。患有内源性抑郁症的患者地塞米松抑制试验不抑制率显著更高，年龄更大，更频繁出现精神病症状，且更频繁体重减轻；即使在控制了这些变量之后，内源性抑郁症组中地塞米松抑制试验不抑制的情况仍显著更频繁。纽卡斯尔评分与地塞米松抑制试验不抑制频率之间的关系是非线性的。
