Department of Operative Dentistry, RAK College of Dental Sciences, RAK Medical and Health Sciences University, Ras Al-Khaimah, United Arab Emirates, Phone: +971 7 2222593(ext-147); +971 58 8204155, e-mail:
Department of Oral and Craniofacial Health Sciences, College of Dental Medicine, University of Sharjah, Sharjah, United Arab Emirates.
J Contemp Dent Pract. 2023 May 1;24(5):278-284. doi: 10.5005/jp-journals-10024-3512.
Silver diamine fluoride (SDF) is a well-known caries preventive aid capable of arresting carious lesions and preventing secondary caries formation. Despite having the caries prevention potential, the clinical use of SDF is limited due to the tooth discoloration caused by SDF. The objective of this study was to evaluate the efficiency of natural antioxidants to inhibit SDF-induced tooth discoloration.
A total of 32 bovine teeth were polished to create a 6 mm circular window on the middle 1/3 (for enamel) or on the cervical 1/3 (for dentin) of the labial surface. Specimens were treated either with SDF alone or SDF followed by ascorbic acid (AA)/alpha lipoic acid (ALA)/7th generation bonding materials. The color parameters Lightness (L*), Chroma (C*), and Hue (H*) of the tooth window were measured at pretreatment, 1-hour, 1-week, and 1-month posttreatment using a digital color chromometer.
Repeated measure ANOVA showed a significant tooth color alteration at 1-hour posttreatment. The L* and H* values dropped and C* value elevated significantly in 1-hour posttreatment measurement. All experimental groups showed significant tooth color alteration after treatment ( < 0.05) and were unable to reverse the discoloration even after 1-month period except the ALA group which did not show any significant ( > 0.05) color alteration compared with the pretreatment value.
Within the limitation of the model and according to the results of this study, it can be concluded that ALA has the potential to prevent SDF-induced tooth discoloration; however, AA was unable to prevent the discoloration.
SDF induces discoloration of enamel and dentin can be reversed by applying Alpha lipoic acid immediacy after SDF application.
银胺氟化物（SDF）是一种众所周知的龋齿预防辅助剂，能够阻止龋齿病变的进展并预防继发龋齿的形成。尽管具有预防龋齿的潜力，但由于 SDF 会导致牙齿变色，其临床应用受到限制。本研究旨在评估天然抗氧化剂抑制 SDF 诱导的牙齿变色的效果。
共 32 颗牛牙被抛光，在唇面的中 1/3（釉质）或颈 1/3（牙本质）处形成一个 6 毫米的圆形窗口。标本单独用 SDF 处理或 SDF 后用抗坏血酸（AA）/α-硫辛酸（ALA）/7 代粘结材料处理。使用数字比色计在预处理、1 小时、1 周和 1 个月后测量牙窗的颜色参数明度（L*）、彩度（C*）和色调（H*）。
重复测量方差分析显示，治疗后 1 小时牙色明显改变。L和 H值在 1 小时后测量时下降，C*值显著升高。所有实验组在治疗后均显示出明显的牙色改变（<0.05），即使经过 1 个月的时间也无法逆转变色，除了 ALA 组，其与预处理值相比没有显示出任何显著的（>0.05）颜色改变。
在模型的限制内，并根据本研究的结果，可以得出结论，ALA 具有预防 SDF 诱导的牙齿变色的潜力；然而，AA 无法预防变色。
SDF 诱导的牙釉质和牙本质变色可以通过在 SDF 应用后立即应用α-硫辛酸来逆转。
