PI «Dnipropetrovsk City Multidisciplinary Clinical Hospital No. 4» DCC, 31 Blyzhnya street, Dnipro, 49102, UkraineDnipro State Medical University, 9, Vernadsky Іtr., Dnipro, 49044, Ukraine.
State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuria Illienka Str., Kyiv, 04050, Ukraine.
Probl Radiac Med Radiobiol. 2023 Dec;28:404-415. doi: 10.33145/2304-8336-2023-28-404-415.
to conduct a comparative analysis of the incidence of malignant oncohematological diseases structure among the population of the 4 most ecologically disadvantaged cities of the Dnipropetrovsk region, taking into account the possible influence of various adverse environmental factors (radiation and chemical pollution of air, water and soil) for the period 2006-2017.
1948 cases of acute myeloblastic and lymphoblastic leukemia, chronic myeloid and lymphocytic leukemia in residents of 4 cities of the Dnipropetrovsk region were analyzed, taking into account the possible influence of adverse environmental factors (radiation, air pollution, etc.). We used clinical and hematological data per patient and statistic information on these diseasis incidence in the region.
An analysis of the oncohematological patients incidence structure, namely: acute lymphoblastic (C91.0) and myeloblastic leukemia (C92.0), chronic lymphocytic (C91.1) and myeloid (C92.1) leukemia, over 12 years in environmentally disadvantaged cities of Dnipropetrovsk region have been conducted. A comparative analysis of the incidence of these diseases among the population of 4 cities of the Dnipropetrovsk region was carried out, taking into account the possible influence of adverse environmental factors (radiation, air pollution, etc.). An excess of the incidence rates of the above-mentioned oncohematological diseases for the period 2006-2017 was revealed in the cities of Dnipro, Kryvyi Rih, Kamianske and Zhovti Vody, where environmental factors significantly affect the increase in morbidity due to pollution mainly by radioactive and chemical substances.
对 2006 年至 2017 年期间，考虑到各种不利环境因素（空气、水和土壤的辐射和化学污染）可能的影响，对第聂伯罗彼得罗夫斯克地区 4 个生态条件最差的城市居民恶性血液肿瘤疾病结构的发病率进行比较分析。
分析了该地区 4 个城市的 1948 例急性髓性和淋巴性白血病、慢性髓性和淋巴细胞性白血病患者，考虑到不利环境因素（辐射、空气污染等）的可能影响。我们使用了每位患者的临床和血液学数据以及该地区这些疾病发病率的统计信息。
对 12 年来处于不利环境条件下的第聂伯罗彼得罗夫斯克地区城市居民血液肿瘤患者的发病率结构（即急性淋巴细胞性（C91.0）和髓性白血病（C92.0）、慢性淋巴细胞性（C91.1）和髓性白血病（C92.1））进行了分析。对第聂伯罗彼得罗夫斯克地区 4 个城市居民的这些疾病发病率进行了比较分析，考虑到不利环境因素（辐射、空气污染等）的可能影响。结果显示，在第聂伯罗、克里维里赫、卡缅斯克和日托米尔等城市，上述血液肿瘤疾病的发病率在 2006 年至 2017 年期间呈上升趋势，环境因素显著影响了由于放射性和化学物质污染而导致的发病率增加。
