曲莫前列素可减少胃酸从人胃中的消失。
Trimoprostil decreases acid disappearance from the human stomach.
作者信息
Penston J G, Johnston D A, Wormsley K G
出版信息
Curr Med Res Opin. 1986;10(5):308-12. doi: 10.1185/03007998609111095.
PMID:3816291
Abstract
A double-blind, placebo-controlled, randomized crossover study involving 8 healthy volunteers was carried out to investigate the disposal of an acid load instilled into the stomach after oral administration of two doses of trimoprostil (0.125 and 1.5 mg). The results showed that trimoprostil reduced the disappearance of acid from the gastric lumen but did not influence the rate of gastric emptying of acid.
摘要
进行了一项双盲、安慰剂对照、随机交叉研究，涉及8名健康志愿者，以调查口服两剂曲莫前列素（0.125毫克和1.5毫克）后注入胃内的酸负荷的处理情况。结果表明，曲莫前列素减少了酸从胃腔中的消失，但不影响胃酸的排空速率。
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