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双侧面神经麻痹为共存的神经莱姆病和急性 COVID-19 后综合征的表现。

Bilateral facial nerve palsy as a presentation of coexisting neuroborreliosis and post-acute COVID-19 syndrome.

机构信息

Ivan Martinez, Department of Neurology, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia,

出版信息

Croat Med J. 2023 Dec 31;64(6):440-443. doi: 10.3325/cmj.2023.64.440.

Abstract

Bilateral simultaneous facial nerve palsy is an extremely rare condition that may be induced by infection (bacterial, viral, or fungal) or noninfective causes (autoimmune, traumatic, or structural). The treatment depends on the underlying disorder, and, if it is introduced on time, the disease is in most cases completely reversible. We report on a patient with bilateral simultaneous facial nerve palsy without an obvious cause. The possible causes were SARS-CoV-2 infection and postvaccination syndrome. After we excluded the SARS-CoV-2 infection, a wide range of diagnostic tests were conducted. Magnetic resonance imaging after gadolinium intravenous application showed bilateral facial nerve enhancement. Serological tests revealed Borrelia burgdorferi, and the result was confirmed by an enzyme-linked immunosorbent assay (IgM positivity). After 14 days of antibiotic therapy, the symptoms resolved completely without sequelae. This report shows that the symptoms of bilateral simultaneous facial nerve palsy may completely resolve if thorough clinical investigation and an appropriate early treatment are applied.

摘要

双侧同时性面神经麻痹是一种极罕见的病症,可能由感染(细菌、病毒或真菌)或非感染性原因(自身免疫、创伤或结构)引起。治疗取决于潜在的疾病,而且,如果及时进行治疗,大多数情况下疾病是完全可逆的。我们报告了一例无明显病因的双侧同时性面神经麻痹患者。可能的病因是 SARS-CoV-2 感染和疫苗接种后综合征。在排除 SARS-CoV-2 感染后,我们进行了广泛的诊断测试。静脉注射钆后磁共振成像显示双侧面神经增强。血清学检查显示伯氏疏螺旋体,酶联免疫吸附试验(IgM 阳性)结果得到证实。抗生素治疗 14 天后,症状完全消退,无后遗症。本报告表明,如果进行彻底的临床检查和适当的早期治疗,双侧同时性面神经麻痹的症状可能完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f519/10797239/90800150a68b/CroatMedJ_64_0440-F1.jpg

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