Keane J R
Department of Neurology, Los Angeles County/University of Southern California Medical Center.
Neurology. 1994 Jul;44(7):1198-202. doi: 10.1212/wnl.44.7.1198.
Among inpatients with facial diplegia, one-half (22 patients) had benign, self-limited causes, including Bell's palsy (10), Guillain-Barré syndrome (5), multiple idiopathic cranial neuropathies (3), brainstem encephalitis (2), Miller Fisher syndrome (1), and association with benign intracranial hypertension (1). Nine patients had tumors: four meningeal, three prepontine, and two intrapontine. Syphilis (2 patients), Hansen's disease (1), cryptococcal meningitis with acquired immunodeficiency syndrome (1), and tuberculous meningitis (1) constituted those with an infectious etiology, while miscellaneous causes included one patient each with diabetes, sarcoidosis, head trauma, pontine tegmental hemorrhage, undiagnosed Möbius syndrome in an adult, systemic lupus erythematosus with severe neuropathy, and slowly progressive degeneration--possibly bulbospinal neuronopathy. Bilaterality makes facial neuropathy a more ominous sign with widely varying causes that requires prompt investigation.
在患有面瘫的住院患者中，一半（22例患者）病因良性且具有自限性，包括贝尔麻痹（10例）、吉兰-巴雷综合征（5例）、多发性特发性颅神经病变（3例）、脑干脑炎（2例）、米勒·费希尔综合征（1例）以及与良性颅内高压相关（1例）。9例患者患有肿瘤：4例为脑膜瘤、3例为桥前肿瘤、2例为桥内肿瘤。梅毒（2例患者）、麻风病（1例）、合并获得性免疫缺陷综合征的隐球菌性脑膜炎（1例）以及结核性脑膜炎（1例）构成了感染性病因，而其他杂类病因包括糖尿病、结节病、头部外伤、脑桥被盖部出血、成人未确诊的莫比乌斯综合征、伴有严重神经病变的系统性红斑狼疮以及缓慢进行性变性（可能为延髓脊髓神经元病）各1例。双侧性使面部神经病变成为一个更凶险的体征，其病因广泛多样，需要及时进行检查。
