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孕期哮喘挑战的综合综述:探究孕早期病情加重情况及先天性异常谱系

A Comprehensive Review on Asthma Challenges in Pregnancy: Exploring First Trimester Exacerbations and the Spectrum of Congenital Anomalies.

作者信息

Yadav Pallavi, Jaiswal Arpita, Patel Archan, Reddy Lucky Srivani, Sindhu Arman

机构信息

Obstetrics and Gynecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Respiratory Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2023 Dec 2;15(12):e49849. doi: 10.7759/cureus.49849. eCollection 2023 Dec.

Abstract

This comprehensive review delves into the intricate relationship between asthma and pregnancy, specifically focusing on the challenges encountered in the first trimester and the ensuing impact on maternal and fetal health. Examining physiological changes during pregnancy reveals the dynamic interplay influencing respiratory function and immune responses. Key findings underscore the vulnerability to asthma exacerbations in the critical first trimester, emphasizing the potential risks to both maternal and fetal well-being. Maternal and fetal outcomes are discussed, emphasizing the associations between poorly controlled asthma and adverse perinatal outcomes. Implications for clinical practice highlight the importance of preconception care, continuous monitoring, and collaborative efforts between obstetricians and pulmonologists. Patient education emerges as a fundamental aspect to empower pregnant women in managing their condition. The conclusion emphasizes the imperative for comprehensive care, advocating for individualized treatment plans, multidisciplinary collaboration, and public health initiatives. By adopting this holistic approach, healthcare providers can navigate the complexities of asthma during pregnancy, ultimately ensuring the optimal health of both the expectant mother and her developing fetus.

摘要

这篇全面综述深入探讨了哮喘与妊娠之间的复杂关系,特别关注孕早期所面临的挑战以及对母婴健康的后续影响。对孕期生理变化的研究揭示了影响呼吸功能和免疫反应的动态相互作用。主要研究结果强调了孕早期这一关键时期哮喘发作的易感性,突出了对母婴健康的潜在风险。文中讨论了母婴结局,强调了哮喘控制不佳与不良围产期结局之间的关联。对临床实践的启示突出了孕前保健、持续监测以及产科医生和肺科医生之间合作的重要性。患者教育成为增强孕妇管理自身病情能力的一个基本方面。结论强调了全面护理的必要性,倡导个性化治疗方案、多学科合作和公共卫生倡议。通过采用这种整体方法,医疗保健提供者可以应对孕期哮喘的复杂性,最终确保准妈妈及其发育中的胎儿的最佳健康。

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