Derman Peter B, Zigler Jack E
Texas Back Institute, Plano, Texas.
Int J Spine Surg. 2020 Aug;14(s2):S5-S13. doi: 10.14444/7086.
Biomechanical studies have demonstrated that cervical fusion results in increased motion and intradiscal pressures at adjacent levels. Cervical disc arthroplasty (CDA) is an alternative treatment for cervical radiculopathy and myelopathy resulting from degenerative disc disease. By maintaining segmental motion, surgeons hope to avoid some of the primary drawbacks of anterior cervical discectomy and fusion (ACDF), such as pseudoarthrosis and adjacent segment disease. First introduced in the 1960s, CDA has evolved over the years with changes to implant geometry and materials. Early devices produced suboptimal outcomes, but more recent generations of implants have shown long-term outcomes rivaling or even surpassing those of ACDF. In this article, the rationale for CDA as well as the history of such devices is reviewed.
生物力学研究表明,颈椎融合会导致相邻节段的活动增加和椎间盘内压力升高。颈椎间盘置换术(CDA)是治疗因椎间盘退变疾病导致的神经根型颈椎病和脊髓型颈椎病的一种替代疗法。通过维持节段性活动,外科医生希望避免前路颈椎间盘切除融合术(ACDF)的一些主要缺点,如假关节形成和相邻节段疾病。CDA最早于20世纪60年代引入,多年来随着植入物几何形状和材料的变化而不断发展。早期的器械产生的效果并不理想,但最近几代植入物已显示出可与ACDF相媲美甚至超越ACDF的长期效果。本文将对CDA的理论依据以及此类器械的历史进行综述。