补充和替代补充剂：雄激素性脱发的皮肤科疗效综述。
Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia.
作者信息
Ufomadu Promise
机构信息
Department of Dermatology and School of Medicine, Baylor College of Medicine, Houston, TX, USA.
出版信息
Proc (Bayl Univ Med Cent). 2023 Dec 20;37(1):111-117. doi: 10.1080/08998280.2023.2263829. eCollection 2024.
BACKGROUND
Androgenetic alopecia (AGA) is a dermatologic condition with no current cure. Treatments such as minoxidil have been proven to be effective; however, the side effects can be unpleasant. As a result, the utilization of natural remedies for treatment has increased over the years. There is limited scientific evidence that addresses the efficacy of these supplements in combating AGA.
METHODS
A review was conducted of the effectiveness of popular complementary and alternative medicines (CAMs) in adult patients experiencing AGA. A literature search was performed for the period of 1993 to 2023 using PubMed, Embase, Google Scholar, Web of Science, and Cochrane.
RESULTS
Natural ingredients like pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, and rosemary oil were effective in treating AGA either when compared to baseline or a definite AGA Western medication, such as minoxidil. These natural agents also presented minimal side effects.
CONCLUSION
Certain CAMs can be promising for hair loss treatment. There is a need for more scientific research to better explore the efficacy of currently identified CAMs in treating AGA.
背景
雄激素性脱发（AGA）是一种目前无法治愈的皮肤病。米诺地尔等治疗方法已被证明有效；然而，其副作用可能令人不适。因此，近年来使用天然疗法进行治疗的情况有所增加。关于这些补充剂对抗AGA疗效的科学证据有限。
方法
对成人AGA患者使用的热门补充和替代药物（CAMs）的有效性进行了综述。使用PubMed、Embase、谷歌学术、科学网和Cochrane对1993年至2023年期间的文献进行了检索。
结果
与基线相比，或与明确的AGA西药如米诺地尔相比，南瓜籽油、锯棕榈、褪黑素提取物、咖啡因提取物和迷迭香油等天然成分在治疗AGA方面有效。这些天然药物的副作用也最小。
结论
某些补充和替代药物在脱发治疗方面可能很有前景。需要更多的科学研究来更好地探索目前已确定的补充和替代药物治疗AGA的疗效。
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