Chinese Center of Exercise Epidemiology, Northeast Normal University, Renmin Street, Changchun, 130024, Jilin, China.
Chinese Center of Exercise Epidemiology, Northeast Normal University, Renmin Street, Changchun, 130024, Jilin, China; AI group, Intelligent Lancet LLC, Sacramento, California, 95816 CA, United States of America; Graduate School of Human Sciences, Waseda University, Tokorozawa, 3591192, Saitama, Japan.
Arch Gerontol Geriatr. 2024 Apr;119:105317. doi: 10.1016/j.archger.2023.105317. Epub 2023 Dec 21.
To improve and even reverse sarcopenia in elderly people, this study developed a self-determined sequence exercise program consisting of strength training exercise, Yijinjing exercise (a traditional Chinese exercise), and hybrid strength training with Yijinjing exercise. Ninety-four community-dwelling older adults screened for sarcopenia using the Asian Working Group for Sarcopenia criteria were randomly assigned to 24 weeks of a control group (CG, n = 30), self-determined sequence exercise program group (SDSG, n = 34) or strength training group (STG, n = 30). The study examined the effects of three interventions on participantsL3 skeletal muscle fat density, L3 skeletal muscle fat area, L3 skeletal muscle density, L3 skeletal muscle area, muscle fat infiltration, relative skeletal muscle mass index, and grip strength using a repeated-measures ANOVA to evaluate the experimental data. To evaluate the real effect of this model in reversing sarcopenia after the intervention, nine classification models were trained. Significant interaction effects were observed with grip strength, RSMI, L3 SMD, and L3 SMA. At the 24th week, participants' grip strength, L3 SMFA, L3 SMA, and RSMI were improved significantly in the SDSG and STG. The SDSG achieved significantly greater RSMI and grip strength than the STG and CG after the intervention. The self-determined sequence exercise program exhibited better performance than the single type of exercise modality in reversing sarcopenia and improving older adults' skeletal muscle area. Consequently, the stacking model is feasible to make a prediction as to whether or not sarcopenia may be reversed in older adults.
为了改善甚至逆转老年人的肌肉减少症，本研究开发了一种自我决定的序列运动方案，包括力量训练运动、易筋经（一种中国传统运动）和易筋经与力量训练的混合运动。本研究共纳入了 94 名符合亚洲肌少症工作组标准的社区老年人，通过自我决定的序列运动方案（SDSG）、力量训练组（STG）和对照组（CG），分别对三组的老年人的 L3 骨骼肌脂肪密度、L3 骨骼肌脂肪面积、L3 骨骼肌密度、L3 骨骼肌面积、肌肉脂肪浸润、相对骨骼肌质量指数和握力进行了为期 24 周的观察。使用重复测量方差分析评估实验数据，结果显示三组干预措施对 L3 骨骼肌脂肪面积、L3 骨骼肌面积、肌肉脂肪浸润、相对骨骼肌质量指数和握力的影响存在显著的交互作用。为了评估该模型在干预后逆转肌肉减少症的真实效果，训练了九个分类模型。结果显示，干预后，SDSG 和 STG 组的握力、RSMI、L3 SMD 和 L3 SMA 均显著提高，且 SDSG 组的 RSMI 和握力显著高于 STG 组和 CG 组。与单一的运动模式相比，自我决定的序列运动方案在逆转肌肉减少症和改善老年人的骨骼肌面积方面表现出更好的效果。因此，堆叠模型可以用于预测老年人是否可能逆转肌肉减少症。
