拉萨链霉菌中醌霉素A的产生
Production of quinomycin A in Streptomyces lasaliensis.
作者信息
Steinerová N, Lipavská H, Stajner K, Cáslavská J, Blumauerová M, Cudlín J, Vanĕk Z
出版信息
Folia Microbiol (Praha). 1987;32(1):1-5. doi: 10.1007/BF02877251.
PMID:3817656
Abstract
In addition to lasalocid, an oligoether coccidiostatic compound, other compounds are synthesized by Streptomyces lasaliensis. Mutants producing either of two antibiotics, lasalocid A or quinomycin A (an antibiotic of quinoxaline character), were obtained by natural selection and by mutagenesis. Methods of isolation, purification and estimation of both compounds were established.
摘要
除了拉沙洛西（一种寡醚类抗球虫化合物）之外，拉萨链霉菌还能合成其他化合物。通过自然选择和诱变获得了产生两种抗生素（拉沙洛西A或喹诺霉素A，一种具有喹喔啉特性的抗生素）之一的突变体。建立了两种化合物的分离、纯化和评估方法。
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