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队列简介:北京老龄化队列研究(BHACS)。

Cohort profile: Beijing Healthy Aging Cohort Study (BHACS).

机构信息

Graduate School, Medical School of Chinese PLA, Beijing, 100853, China.

Institute of Geriatrics, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatrics Diseases, Second Medical Center, Chinese PLA General Hospital, Beijing, 100853, China.

出版信息

Eur J Epidemiol. 2024 Jan;39(1):101-110. doi: 10.1007/s10654-023-01050-z. Epub 2024 Jan 4.

Abstract

The Beijing Healthy Aging Cohort Study (BHACS) was established to supplement the limited data of a large representative cohort of older people based on the general population and was designed to evaluate the prevalence, incidence, and natural history of cognitive decline, functional disability, and conventional vascular risk factors. The aim was to determine the evolution of these conditions by estimating the rates and determinants of progression and regression to adverse outcomes, including dementia, cardiovascular events, cancer, and all-cause death. It can therefore provide evidence to help policy makers develop better policies to promote healthy aging in China. BHACS consisted of three cohorts (BLSA, CCHS-Beijing, and BECHCS) in Beijing with a total population of 11 235 (6281 in urban and 4954 in rural areas) and an age range of 55 years or older (55-101 years) with a mean age of 70.35 ± 7.71 years (70.69 ± 7.62 years in urban and 69.92 ± 7.80 years in rural areas). BHACS-BLSA conducted the baseline survey in 2009 with a multistage stratification-random clustering procedure for people aged 55 years or older; BHACS-CCHS-Beijing conducted the baseline survey in 2013-2015 with a stratified multistage cluster random sampling method for people aged 55 years or older; and BHACS-BECHCS conducted the baseline survey in 2010-2014 with two-stage cluster random sampling method for people aged 60 years or older. Data were collected through questionnaires, physical measurements, and laboratory analyses. Topics covered by BHACS include a wide range of physical and mental health indicators, lifestyles and personal, family, and socio-economic determinants of health. There are no immediate plans to make the cohort data freely available to the public, but specific proposals for further collaboration are welcome. For further information and collaboration, please contact the corresponding author Yao He (e-mail: yhe301@x263.net).

摘要

北京老年队列研究(BHACS)旨在补充基于一般人群的大型代表性老年人队列中有限的数据,评估认知能力下降、功能障碍和常规血管风险因素的流行率、发病率和自然史。其目的是通过估计进展和回归不良结局(包括痴呆、心血管事件、癌症和全因死亡)的速度和决定因素来确定这些情况的演变,从而为政策制定者提供帮助,制定更好的政策来促进中国的健康老龄化。BHACS 由北京的三个队列(BLSA、CCHS-北京和 BECHCS)组成,共有 11235 人(城市 6281 人,农村 4954 人),年龄在 55 岁及以上(55-101 岁),平均年龄为 70.35 ± 7.71 岁(城市 70.69 ± 7.62 岁,农村 69.92 ± 7.80 岁)。BHACS-BLSA 于 2009 年采用多阶段分层随机聚类程序对 55 岁及以上人群进行了基线调查;BHACS-CCHS-北京于 2013-2015 年采用分层多阶段聚类随机抽样方法对 55 岁及以上人群进行了基线调查;BHACS-BECHCS 于 2010-2014 年采用两阶段聚类随机抽样方法对 60 岁及以上人群进行了基线调查。数据通过问卷、体格测量和实验室分析收集。BHACS 涵盖的主题广泛,包括身心健康指标、生活方式以及个人、家庭和社会经济健康决定因素。目前尚无向公众免费提供队列数据的计划,但欢迎提出进一步合作的具体建议。如需进一步信息和合作,请联系通讯作者姚赫(电子邮箱:yhe301@x263.net)。

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