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基层医疗环境中健康老龄化治疗核心结局集的制定。

Development of core outcome set for healthy aging treatment in primary care settings.

作者信息

Jang Soobin, Jeong Hyein, Park Jungi, Ko Mi Mi, Jung Jeeyoun

机构信息

Department of Preventive Medicine, College of Korean Medicine, Daegu Hanny University, Gyeongsan, Korea.

Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea.

出版信息

Integr Med Res. 2025 Dec;14(4):101205. doi: 10.1016/j.imr.2025.101205. Epub 2025 Jul 19.

Abstract

BACKGROUND

Healthy aging is a global public health priority, with increasing interest in the promotion of functional ability and well-being among older adults. South Korea's rapidly aging population highlights the need for standardized evaluation tools for interventions. This study aimed to develop a Core Outcome Set (COS) for healthy aging treatment in primary care.

METHODS

The COS was developed following the COS-STAD guidelines and through a multiphase process, including a literature review and a modified Delphi consensus. A project management group (PMG) reviewed studies related to health promotion programs and generated an initial list of outcomes. This list was refined through two rounds of Delphi surveys involving 16 experts. Consensus was assessed using content validity ratio, degree of consensus, and convergence.

RESULTS

Twenty-six studies informed the initial outcome list, resulting in 24 outcomes for the Delphi evaluation. Two Delphi rounds and a final review by the PMG established a COS comprising 12 outcomes. These included EQ-5D, Geriatric Depression Scale, Instrumental Activities of Daily Living, body weight, blood pressure, blood glucose, blood lipids, liver function, kidney function, Korean Frailty Index, Self-rated Health, and Kidney-Deficiency Score.

CONCLUSIONS

The COS provides a standardized set of outcomes for evaluating healthy aging interventions in primary care. Its application in primary care and health promotion programs may enhance comparability across studies and support evidence-based decision making. Future revisions are recommended based on clinical applications and emerging research findings.

摘要

背景

健康老龄化是全球公共卫生的重点,人们对促进老年人的功能能力和幸福感的关注度日益提高。韩国人口迅速老龄化凸显了对干预措施进行标准化评估工具的需求。本研究旨在制定基层医疗中健康老龄化治疗的核心结局集(COS)。

方法

COS是按照COS-STAD指南并通过多阶段过程制定的,包括文献综述和改良的德尔菲共识法。一个项目管理小组(PMG)对与健康促进计划相关的研究进行了审查,并生成了一份初始结局清单。通过两轮涉及16名专家的德尔菲调查对该清单进行了完善。使用内容效度比、共识程度和收敛性来评估共识。

结果

26项研究为初始结局清单提供了信息,从而产生了24项用于德尔菲评估的结局。两轮德尔菲调查和PMG的最终审查确定了一个由12项结局组成的COS。这些包括EQ-5D、老年抑郁量表、日常生活活动能力、体重、血压、血糖、血脂、肝功能、肾功能、韩国衰弱指数、自评健康和肾虚评分。

结论

COS为评估基层医疗中的健康老龄化干预措施提供了一套标准化的结局。其在基层医疗和健康促进计划中的应用可能会提高各研究之间的可比性,并支持基于证据的决策制定。建议根据临床应用和新出现的研究结果进行未来修订。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b893/12391697/2c279b3125bd/gr1.jpg

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