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钛泡沫上制备的有序 TiO2 纳米管表面的表面特性和抗菌效率。

Surface characterization and antibacterial efficiency of well-ordered TiO nanotube surfaces fabricated on titanium foams.

机构信息

Department of Industrial Engineering, Engineering Faculty, Giresun University, 28200, Giresun, Turkey.

Department of Materials and Metallurgical Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.

出版信息

Sci Rep. 2024 Jan 5;14(1):618. doi: 10.1038/s41598-024-51339-6.

Abstract

Titanium (Ti)-based implants are not compatible enough due to their bio-inert character, insufficient antibacterial capabilities and stress-shielding problem for dental and orthopaedic implant applications. Thus, this work focused to fabricate, analyze and improve antibacterial properties titanium dioxide (TiO) nanotube array surfaces on Ti foam by anodic oxidation (AO) process. The well-ordered nanotube arrays with approximately 75 nm were successfully fabricated at 40 V for 1 h on Ti foams. Ti and O were observed as major elements on AO-coated Ti foam surfaces. In addition, the existence of TiO structure was proved on AO-coated foam Ti surfaces. For potential dental and orthopedic implant application, in vitro antibacterial properties were investigated versus Staphylococcus aureus and Escherichia coli. For both bacteria, antibacterial properties of TiO nanotube surface were greater than bare Ti foam. The bacterial inhibition versus Staphylococcus aureus and Escherichia coli of TiO nanotube surfaces are improved as 53.3% and 69.4% compared to bare Ti foam.

摘要

钛(Ti)基植入物由于其生物惰性、抗菌能力不足以及在牙科和骨科植入物应用中的应力屏蔽问题,兼容性不够。因此,这项工作专注于通过阳极氧化(AO)工艺在钛泡沫上制造、分析和改善二氧化钛(TiO)纳米管阵列表面的抗菌性能。在钛泡沫上以 40 V 处理 1 小时,成功制备了具有约 75nm 的规则纳米管阵列。在 AO 涂层的 Ti 泡沫表面观察到 Ti 和 O 是主要元素。此外,在 AO 涂层泡沫 Ti 表面上证明了 TiO 结构的存在。对于潜在的牙科和骨科植入物应用,研究了对金黄色葡萄球菌和大肠杆菌的体外抗菌性能。对于这两种细菌,TiO 纳米管表面的抗菌性能均优于裸 Ti 泡沫。与裸 Ti 泡沫相比,TiO 纳米管表面对金黄色葡萄球菌和大肠杆菌的抑菌率分别提高了 53.3%和 69.4%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c2b/10770057/9bc725c6a616/41598_2024_51339_Fig1_HTML.jpg

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