Munteanu Iurii, Mihaela Munteanu, Popescu Silvia, Slavu Iulian M, Oprescu Macovei Anca, Cochior Daniel
General Surgery, Lotus Hospital, Ploiesti, ROU.
Radiology, CF2 Clinical Hospital, Bucharest, ROU.
Cureus. 2023 Dec 6;15(12):e50079. doi: 10.7759/cureus.50079. eCollection 2023 Dec.
Colorectal polyps, frequently adenomas, are common in older adults, with villous adenomas being a notable subset due to their potential for significant malignancy risk. This case report highlights a rare instance of a giant villous adenoma in a 79-year-old female patient, challenging in both diagnosis and treatment. The patient, with a history of untreated essential arterial hypertension, was hospitalized for severe anemia following a massive rectal hemorrhage. An irreducible, prolapsed rectal mass was evident upon examination, and further investigations, including rectoscopy and abdominopelvic computed tomography scan, confirmed a villous adenoma with severe dysplasia. Given the tumor's substantial size, circumferential nature, and proximity to the dentate line, an abdominoperineal resection using the Miles technique was performed. The histopathological examination post-surgery confirmed the presence of a villous adenoma with high-grade epithelial neoplasia and localized areas of well-differentiated tubular adenocarcinoma. This case underscores the diagnostic and management complexities of large villous adenomas, emphasizing the need for meticulous surgical decision-making to ensure oncological safety and patient welfare, particularly when conservative resection may be inadequate.
结直肠息肉,通常为腺瘤,在老年人中很常见,绒毛状腺瘤因其具有显著的恶性风险潜力而成为一个值得注意的亚组。本病例报告突出了一名79岁女性患者罕见的巨大绒毛状腺瘤病例,在诊断和治疗方面都具有挑战性。该患者有未经治疗的原发性动脉高血压病史,因大量直肠出血后严重贫血而住院。检查时可见一个无法回纳的直肠脱垂肿物,进一步检查,包括直肠镜检查和腹盆腔计算机断层扫描,证实为伴有严重发育异常的绒毛状腺瘤。鉴于肿瘤体积巨大、呈环形且靠近齿状线,采用Miles技术进行了腹会阴切除术。术后组织病理学检查证实存在绒毛状腺瘤伴高级别上皮内瘤变以及局部高分化管状腺癌区域。该病例强调了大型绒毛状腺瘤诊断和管理的复杂性,强调需要进行细致的手术决策以确保肿瘤学安全性和患者福祉,特别是在保守切除可能不充分的时候。