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针对成年智障人士的整群随机对照试验中的体重减轻与饮食改善

Weight reduction and dietary improvements in a cluster-randomised controlled trial for adults with intellectual disabilities.

作者信息

Røstad-Tollefsen Helen K, Kolset Svein O, Retterstøl Kjetil, Hesselberg Heidi, Nordstrøm Marianne

机构信息

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Baerum Municipality, Housing, Activity and Organized Work, Health, and Welfare, Baerum, Norway.

出版信息

Food Nutr Res. 2023 Dec 19;67. doi: 10.29219/fnr.v67.9505. eCollection 2023.

Abstract

BACKGROUND

People with intellectual disabilities (IDs) have an increased risk of obesity and health concerns related to their nutritional status and dietary intake.

OBJECTIVE

To assess the effectiveness of a multi-component intervention on weight, waist circumference (WC), clinical health parameters and dietary habits in a group of overweight and obese adults with mild-to-moderate ID.

DESIGN

A 7-month cluster-randomised trial and a 7-month follow-up of the intervention group after the end of intervention when the group received usual care. The intervention consisted of monthly dietary-group courses tailored to the participants' cognitive abilities and practical skills, monthly nutritional courses for staff, use of behaviour change techniques and nudging. The control group received usual care during the intervention.

RESULTS

There were 32 participants aged 22-61 years: 15 in the intervention group and 17 in the control group. After 7 months, a non-significant weight difference (median difference = -1.25 kg; 95% confidence interval [CI] = -2.00; 0.95 vs. +1.00 kg; CI = -1.15; 3.00, = 0.08) and a significant WC difference were observed between the intervention and control groups (median difference = -3.75 cm; CI: -7.68; 0.11 vs. 0 cm; CI = -3.99; 1.00, = 0.03), respectively. The median reduction in WC continued in the intervention group during the 7-month follow-up (median difference = -7.50 cm; CI: -13.57; -3.16, = 0.002). A significant difference in frequency intake of fruit ( = 0.03) and berries ( = 0.004) was observed between the groups after 7 months, supported by a significant increase in measured serum-carotenoid levels in the intervention group after 7 months (median difference = 0.26 mmol/L; CI: -0.12; 0.52, = 0.007).

CONCLUSIONS

A significant difference in WC was observed between the groups, accompanied by changes in blood parameters and dietary habits.

摘要

背景

智力残疾者肥胖风险增加,且存在与营养状况和饮食摄入相关的健康问题。

目的

评估多成分干预措施对一组轻度至中度智力残疾的超重和肥胖成年人的体重、腰围(WC)、临床健康参数及饮食习惯的效果。

设计

一项为期7个月的整群随机试验,以及干预组在干预结束后接受常规护理时为期7个月的随访。干预措施包括根据参与者的认知能力和实践技能量身定制的每月饮食小组课程、为工作人员开设的每月营养课程、行为改变技术的应用及助推。对照组在干预期间接受常规护理。

结果

共有32名年龄在22至61岁之间的参与者:干预组15人,对照组17人。7个月后,干预组与对照组之间体重差异无统计学意义(中位数差异=-1.25千克;95%置信区间[CI]=-2.00;0.95对比+1.00千克;CI=-1.15;3.00,P=0.08),但腰围差异有统计学意义(中位数差异=-3.75厘米;CI:-7.68;0.11对比0厘米;CI=-3.99;1.00,P=0.03)。在为期7个月的随访期间,干预组腰围的中位数持续下降(中位数差异=-7.50厘米;CI:-13.57;-3.16,P=0.002)。7个月后,两组之间水果(P=0.03)和浆果(P=0.004)的摄入频率存在显著差异,干预组7个月后测得的血清类胡萝卜素水平显著升高(中位数差异=0.26毫摩尔/升;CI:-0.12;0.52,P=0.007)支持了这一结果。

结论

两组之间腰围存在显著差异,同时伴有血液参数和饮食习惯的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9725/10770699/f2c31fd210ac/FNR-67-9505-g001.jpg

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