Kaneko S, Maruyama T
J Clin Microbiol. 1987 Feb;25(2):454-5. doi: 10.1128/jcm.25.2.454-455.1987.
It is known that Yersinia enterocolitica infection in Japan is caused mainly by serotype O3 biotype 4 strains. Recently, however, a number of serotype O3 strains which were classified biotype 3 and which ferment lactose and xylose, instead of sorbose, and give a negative Voges-Proskauer reaction have been isolated from both humans and animals. In this study, comparisons of four properties were made among isolates of Y. enterocolitica serotype O3 biotype 3 from humans, pigs, dogs, cats, and rats and the laboratory stock strains of Y. enterocolitica biotype 4. All strains were tested for the presence of plasmids, calcium-dependent growth at 37 degrees C, autoagglutination activity at 37 degrees C, and recovery of the organisms from the stools of intravenously challenged mice. Biotypes 3 and 4 were positive for these four properties. Plasmid digestion with restriction endonucleases showed the same digestion patterns in both biotypes. These results suggest that Y. enterocolitica serotype O3 biotype 3 strains are pathogenic, as are biotype 4 strains.
已知在日本，小肠结肠炎耶尔森氏菌感染主要由O3血清型4生物型菌株引起。然而，最近从人和动物中分离出了许多O3血清型菌株，这些菌株被归类为生物型3，它们发酵乳糖和木糖而非山梨糖，且Voges-Proskauer反应呈阴性。在本研究中，对来自人、猪、狗、猫和大鼠的小肠结肠炎耶尔森氏菌O3血清型3生物型分离株与小肠结肠炎耶尔森氏菌生物型4的实验室储备菌株进行了四项特性的比较。对所有菌株进行了质粒存在情况、37℃下钙依赖性生长、37℃下自凝活性以及从静脉内攻击小鼠粪便中回收细菌的检测。生物型3和4在这四项特性上均呈阳性。用限制性内切酶进行质粒消化显示两种生物型的消化模式相同。这些结果表明，小肠结肠炎耶尔森氏菌O3血清型3生物型菌株与生物型4菌株一样具有致病性。
