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用于治疗 6 至 59 月龄儿童中度急性营养不良的即食食品补充剂的疗效。

Efficacy of ready-to-use food supplement for treatment of moderate acute malnutrition among children aged 6 to 59 months.

机构信息

Department of Nutrition Education and Training (NET), Tanzania Food and Nutrition Centre, Dar es salaam, Tanzania.

Department of Food Science and Agroprocessing, Sokoine University of Agriculture, Morogoro, Tanzania.

出版信息

Matern Child Nutr. 2024 Apr;20(2):e13602. doi: 10.1111/mcn.13602. Epub 2024 Jan 8.

DOI:10.1111/mcn.13602
PMID:38192064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10981477/
Abstract

Moderate acute malnutrition (MAM) is a persistent public health problem in Tanzania. The current approach for its management is nutrition counselling. However, there has been no commercial production of ready-to-use supplementary foods for the management of MAM in the country but rather imported from companies outside the country. The objective of the study was to determine the ability of a ready-to-use food supplementation versus corn soya blend (CSB+) to manage MAM. The randomised controlled trial employed three parallel arm approach. The first arm received CSB+ and infant and young child feeding (IYCF) counselling, the second arm received ready-to-use food (RUF) and IYCF counselling and the third arm, a control group, received IYCF as standard care for three consecutive months. Results indicated that the overall proportion of children who recovered from MAM was 65.6%. There was a significant difference (p < 0.001) in the proportion of children who recovered from MAM between the three arms (CSB+, RUF and standard care). Results revealed further a high recovery rate of 83.7% in the RUF arm, followed by 71.9% in the CSB+ arm and 41% in the standard care arm. The risk differences for RUF compared with CSB+ and standard care were 11.8% and 42.7%, respectively. RUFs can be used as an alternative supplement to conventional CSB+ for the management of MAM in children and, thus, has the potential to scale up its use to address the problem of MAM among 6 to 59 months' children.

摘要

中度急性营养不良(MAM)是坦桑尼亚长期存在的公共卫生问题。目前对此的管理方法是营养咨询。然而,该国尚未进行商业化生产用于管理 MAM 的即食补充食品,而是从国外公司进口。本研究的目的是确定即食食品补充剂与玉米大豆混合物(CSB+)在管理 MAM 方面的效果。这项随机对照试验采用了三臂平行的方法。第一组接受 CSB+和婴幼儿喂养(IYCF)咨询,第二组接受即食食品(RUF)和 IYCF 咨询,第三组为对照组,接受 IYCF 作为标准护理,连续三个月。结果表明,从 MAM 中康复的儿童比例总体为 65.6%。在接受 CSB+、RUF 和标准护理的三组之间,从 MAM 中康复的儿童比例存在显著差异(p<0.001)。结果进一步显示,RUF 组的康复率高达 83.7%,CSB+组为 71.9%,标准护理组为 41%。与 CSB+和标准护理相比,RUF 的风险差异分别为 11.8%和 42.7%。RUF 可作为常规 CSB+的替代品,用于治疗儿童 MAM,因此有可能扩大其使用范围,以解决 6 至 59 个月儿童的 MAM 问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6433/10981477/37f027ce52e1/MCN-20-e13602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6433/10981477/37f027ce52e1/MCN-20-e13602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6433/10981477/37f027ce52e1/MCN-20-e13602-g002.jpg

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2
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3
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