Maroudas A, Schneiderman R
J Orthop Res. 1987;5(1):133-8. doi: 10.1002/jor.1100050117.
We repeated some of our own previous experiments, as well as some of Torzilli's recent experiments (11) on which he bases his conclusions relating to a nonexchangeable "trapped water" in cartilage. We are unable to confirm Torzilli's findings. We observed partition coefficients for 3H.HO very close to unity. That both the extrafibrillar and most of the intrafibrillar water is freely exchangeable and behaves as available water towards small solutes has been independently shown (3) for other collagenous tissues. All the different permutations of partition experiments have yielded results that are fully consistent with our original picture of the very major fraction of cartilage water being free.
我们重复了我们自己之前的一些实验，以及托尔齐利最近的一些实验（11），他基于这些实验得出了与软骨中不可交换的“滞留水”相关的结论。我们无法证实托尔齐利的发现。我们观察到3H.HO的分配系数非常接近1。对于其他胶原组织，已经独立证明（3）细胞外和大部分细胞内的水都是可自由交换的，并且对小溶质表现为可用水。分配实验的所有不同排列都产生了与我们最初认为软骨水的绝大部分是自由水的观点完全一致的结果。
