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健康生活方式与结直肠癌术后患者生活质量的关系:一项为期五个月的观察性研究。

Healthy Lifestyle and Quality of Life in Post-Operative Colorectal Cancer Patients: A Five-Month Observational Study.

机构信息

Division of Colorectal, Department of Surgery, MacKay Memorial Hospital, Taipei City 10449, Taiwan.

MacKay Junior College of Medicine Nursing and Management, Taipei City 11260, Taiwan.

出版信息

Nutrients. 2023 Dec 25;16(1):68. doi: 10.3390/nu16010068.

Abstract

Health-related quality of life (HRQOL) is an important indicator of treatment effectiveness. An unhealthy lifestyle can have a negative impact on quality of life. This study aimed to investigate changes in health-related lifestyle over time after surgery for colorectal cancer and their impact on HRQOL. Healthy lifestyle habits examined in this study included physical activity, smoking, alcohol consumption, fruit and vegetable intake, sleep, and obesity levels. An observational study design was used. A total of 75 post-operative colorectal cancer patients were recruited from two medical centers in Taiwan. Data were collected through structured questionnaires. Mean HRQOL scores at 1, 3, and 5 months after discharge were 102.5 (SD = 18.8), 102.9 (SD = 20.1), and 103.0 (SD = 18.9), respectively. A generalized estimating equation analysis showed that alcohol consumption ( = 0.009), fruit and vegetable intake ( = 0.020), physical activity ( = 0.023), sleep quality ( < 0.001), and obesity ( = 0.035) were important predictors of post-operative quality of life in patients with colorectal cancer. The impact of smoking on HRQOL did not reach statistical significance. Colorectal cancer patients tend to have better HRQOL after surgery if they stay physically active, eat enough fruits and vegetables, and sleep well.

摘要

健康相关生活质量(HRQOL)是治疗效果的重要指标。不健康的生活方式会对生活质量产生负面影响。本研究旨在探讨结直肠癌手术后生活方式随时间的变化及其对 HRQOL 的影响。本研究中检查的健康生活习惯包括身体活动、吸烟、饮酒、水果和蔬菜摄入、睡眠和肥胖水平。采用观察性研究设计。共招募了来自台湾两家医疗机构的 75 名术后结直肠癌患者。通过结构化问卷收集数据。出院后 1、3 和 5 个月的平均 HRQOL 评分分别为 102.5(SD=18.8)、102.9(SD=20.1)和 103.0(SD=18.9)。广义估计方程分析显示,饮酒(=0.009)、水果和蔬菜摄入(=0.020)、身体活动(=0.023)、睡眠质量(<0.001)和肥胖(=0.035)是结直肠癌患者术后生活质量的重要预测因素。吸烟对 HRQOL 的影响没有达到统计学意义。如果结直肠癌患者保持身体活跃、摄入足够的水果和蔬菜以及睡眠良好,他们在手术后往往会有更好的 HRQOL。

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