Chapman M L, Rubin B R, Gracy R W
J Rheumatol. 1986 Oct;13(5):850-2.
Our study was designed to quantitate levels of NAD+, NADH, NADP(H), and ATP in peripheral blood lymphocytes with and without mitogenic stimulation from patients with rheumatoid arthritis (RA). No differences were found in patients with RA and healthy controls. Our data suggest the ability of the redox system of circulating peripheral lymphocytes to respond to mitogenic stimulation in patients with RA is not markedly impaired.
我们的研究旨在定量检测类风湿关节炎（RA）患者有丝分裂原刺激和无丝分裂原刺激时外周血淋巴细胞中NAD⁺、NADH、NADP（H）和ATP的水平。在RA患者和健康对照者中未发现差异。我们的数据表明，RA患者循环外周淋巴细胞氧化还原系统对有丝分裂原刺激作出反应的能力未受到明显损害。
