Thompson P, Herndon D N, Abston S, Rutan T
J Trauma. 1987 Feb;27(2):205-7. doi: 10.1097/00005373-198702000-00019.
A randomized study was carried out to determine the effect on mortality of early massive excision of large burns. Fifty consecutive adult patients admitted to our hospital burn unit between December 1983 and January 1986 with 2 degrees and 3 degrees burns totaling at least 30% total body surface area (TBSA) were randomized on admission to one of two groups. The patients received either conservative therapy or early massive excision of all full-thickness burns. The two groups were similar in average size of burn but differed in their average age. In the patients with burns greater than 50% TBSA and no inhalation injury, mortality was decreased with early excision, which can be explained entirely by age differences alone. There was not a significant difference in length of stay, blood requirements, or in mortality in other groups of patients.
进行了一项随机研究，以确定早期大面积切除大面积烧伤对死亡率的影响。1983年12月至1986年1月期间，连续50名成年患者因二度和三度烧伤入院，我院烧伤科收治的烧伤总面积至少为30%体表面积（TBSA）的患者在入院时被随机分为两组。患者接受保守治疗或早期大面积切除所有全层烧伤。两组患者的平均烧伤面积相似，但平均年龄不同。在烧伤面积大于50%TBSA且无吸入性损伤的患者中，早期切除可降低死亡率，这完全可以仅由年龄差异来解释。其他患者组在住院时间、血液需求量或死亡率方面没有显著差异。
