Ramón y Cajal S, Piñango L, Barat A, Moldenhauer F, Oliva H
J Urol. 1987 Mar;137(3):516-9. doi: 10.1016/s0022-5347(17)44095-x.
The case described of pure choriocarcinoma of the testis is rare because of the histological type and patient age at presentation. A 63-year-old man had a 160 gm. tumor, with a necrotic, hemorrhagic appearance and sparse bright areas that consisted exclusively of syncytial and cytotrophoblastic cells. Immunocytochemical analysis revealed strong staining for human chorionic gonadotropin in the syncytiotrophoblastic cells. The specimen was moderately positive for keratin and negative for alpha-fetoprotein.
由于组织学类型和就诊时患者年龄的原因,睾丸纯绒毛膜癌的病例较为罕见。一名63岁男性患有一个160克的肿瘤,外观呈坏死、出血状,有稀疏的明亮区域,仅由合体滋养层细胞和细胞滋养层细胞组成。免疫细胞化学分析显示合体滋养层细胞中人绒毛膜促性腺激素染色强烈。该标本角蛋白呈中度阳性,甲胎蛋白呈阴性。