Lin Diwei, Tan Amanda Jia Hui, Singh-Rai Rajinder
Division of Surgery, Lyell McEwin Hospital, Adelaide, SA, Australia.
Case Rep Oncol Med. 2015;2015:345018. doi: 10.1155/2015/345018. Epub 2015 Nov 16.
In 2012, testicular cancer was estimated to account for 940 disability adjusted life years in Australia; of these, 450 were years lost due to premature death and 500 were years of healthy life lost due to disease, disability, or injury (Australian Institute of Health and Welfare and Australasian Association of Cancer Registries, 2012). Testicular choriocarcinoma is one of the rarest variants of testicular germ cell tumours, accounting for less than 1% of testicular germ cell tumours and only about 0.19% of all testicular tumours. Management involves radical orchidectomy and chemotherapy. Even then, prognosis is poor. This case report describes a 20-year-old male with pure testicular choriocarcinoma with pulmonary metastases which showed sustained and complete response to adjuvant chemotherapy consisting of bleomycin, etoposide, and cisplatin.
2012年,据估计睾丸癌在澳大利亚导致940个伤残调整生命年;其中,450个是因过早死亡而损失的年份,500个是因疾病、残疾或损伤而损失的健康生命年份(澳大利亚卫生与福利研究所及澳大利亚癌症登记协会,2012年)。睾丸绒毛膜癌是睾丸生殖细胞肿瘤中最罕见的变体之一,占睾丸生殖细胞肿瘤的比例不到1%,仅占所有睾丸肿瘤的约0.19%。治疗包括根治性睾丸切除术和化疗。即便如此,预后仍很差。本病例报告描述了一名20岁男性患有纯睾丸绒毛膜癌并伴有肺转移,该患者对由博来霉素、依托泊苷和顺铂组成的辅助化疗表现出持续且完全的反应。